Known targets — ChEMBL curated mechanism
ACHEADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3APH1AAPH1BCHRM2CHRM3EZH2GRIN2AHTR1AHTR1BHTR1DHTR1FHTR3ANCSTNP2RY12PSEN1PSEN2PSENENSIGMAR1SLC6A2SLC6A3SLC6A4
The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29587 | 0.96 | TSHR (0.33) | TSHRALDH1A1 | |
| Charcoal, Activated SCHEMBL7745778 | 0.92 | TSHR (0.31) | TSHRALDH1A1 | |
| SCHEMBL569476 | 0.92 | TSHR (0.31) | TSHRALDH1A1 | |
| Hydrogen Sulfide SCHEMBL28434446 | 0.92 | TSHR (0.31) | TSHRALDH1A1 | |
| Hydrochloric Acid SCHEMBL709785 | 0.92 | TSHR (0.31) | TSHRALDH1A1 | |
| Hydrochloric Acid SCHEMBL15569340 | 0.92 | TSHR (0.31) | TSHRALDH1A1 | |
| SCHEMBL28401032 | 0.92 | TSHR (0.31) | TSHRALDH1A1 | |
| SCHEMBL9413747 | 0.92 | TSHR (0.31) | TSHRALDH1A1 | |
| Water SCHEMBL4565708 | 0.92 | TSHR (0.31) | TSHRALDH1A1 | |
| SCHEMBL28399385 | 0.92 | TSHR (0.31) | TSHRALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 31 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024073209-A1 | MODIFIED WATER-SOLUBLE POLYSACCHARIDES HAVING DIFFERENT CATION TYPES FOR SLURRIES IN CHEMICAL MECHANICAL PLANARIZATION | VERSUM MATERIALS US, LLC (US) | 2024-04-04 | — | — | WO | claimed |
| US-20140288266-A1 | Synthesis of Cyclosporin Analogs | AURINIA PHARMACEUTICALS, INC. (CA) | 2014-09-25 | — | — | US | disclosed |
| EP-2125829-B1 | BICYCLIC OXOMORPHOLINE DERIVATIVE | EISAI R&D MAN CO LTD (JP) | 2013-01-16 | — | — | EP | disclosed |
| CN-101622258-B | Bicyclic oxomorpholine derivatives | EISAI R&D MAN CO LTD | 2012-06-13 | — | — | CN | disclosed |
| US-8008293-B2 | Bicyclic oxomorpholine derivative | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2011-08-30 | — | — | US | disclosed |
| US-20110092669-A1 | SYNTHESIS OF CYCLOSPORIN ANALOGS | ISOTECHNIKA INC. (CA) | 2011-04-21 | — | — | US | disclosed |
| US-20100113773-A1 | BICYCLIC OXOMORPHOLINE DERIVATIVE | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2010-05-06 | — | — | US | disclosed |
| US-20100062976-A1 | Synthesis of Cyclosporin Analogs | ISOTECHNIKA INC. (CA) | 2010-03-11 | — | — | US | disclosed |
| CN-101622258-A | Bicyclic oxomorpholine derivatives | EISAI R&D MAN CO LTD | 2010-01-06 | — | — | CN | disclosed |
| EP-2125829-A2 | BICYCLIC OXOMORPHOLINE DERIVATIVE | Eisai R&D Management Co., Ltd. (JP) | 2009-12-02 | — | — | EP | disclosed |
| US-6881478-B2 | Polyketone fiber and process for producing the same | ASAHI KASEI KABUSHIKI KAISHA (JP) | 2005-04-19 | — | — | US | disclosed |
| US-20050031864-A1 | Polyketone fiber and process for producing the same | ASAHI KASEI KABUSHIKI KAISHA | 2005-02-10 | — | — | US | disclosed |
| US-6818728-B2 | HIGH STRENGTH; ELASTICITY; VISCOSITY; FATIGUQ RESISTANCE; PROCESSABILITY; HEAT RESISTANCE; DIMENSIONAL STABILITY; FOR REINFORCED COMPOSITES FOR TIRES, CORDS, BELTS, HOSES, OR BUILDING MATERIALS | ASAHI KASEI KABUSHIKI KAISHA (JP) | 2004-11-16 | — | — | US | disclosed |
| EP-1436321-A2 | SYNTHESIS OF CYCLOSPORIN ANALOGS | Isotechnika Inc. (CA) | 2004-07-14 | — | — | EP | disclosed |
| EP-1371759-A1 | POLYKETONE FIBER AND PROCESS FOR PRODUCING THE SAME | Asahi Kasei Kabushiki Kaisha (JP) | 2003-12-17 | — | — | EP | disclosed |
| US-20030212249-A1 | Synthesis of cyclosporin analogs | ISOTECHNIKA, INC. (CA) | 2003-11-13 | — | — | US | disclosed |
| WO-2003033526-A2 | SYNTHESIS OF CYCLOSPORIN ANALOGS | ISOTECHNIKA INC. (CA) | 2003-04-24 | — | — | WO | disclosed |
| US-20030026981-A1 | Polyketone fiber and process for producing the same | ASAHI KASEI KABUSHIKI KAISHA | 2003-02-06 | — | — | US | disclosed |
| US-3987082-A | PROSTAGLANDIN INTERMEDIATE | MERCK & CO., INC. (US) | 1976-10-19 | — | — | US | disclosed |
| US-3950359-A | PROSTAGLANDINS AND METHODS OF MAKING SAME | MERCK & CO., INC. (US) | 1976-04-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100113773-A1 | BICYCLIC OXOMORPHOLINE DERIVATIVE | OPRM1, OPRK1, OPRD1 | TSHR 729/4885ALDH1A1 1360/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.