SCHEMBL1654017

SCHEMBL1654017

CCOC(=O)C1(C(=O)O)CCC1

nearest known ligand 0.52

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 1/20 0.46
MEN1 O00255 2/20 0.41
KMT2A Q03164 2/20 0.41
OPRM1 P35372 6/20 0.39
OPRD1 P41143 3/20 0.38
OPRK1 P41145 3/20 0.38
SLC22A1 O15245 1/20 0.38
SLC6A4 P31645 1/20 0.38
ADRA1A P35348 1/20 0.38
KCNH2 Q12809 1/20 0.38
ALOX15 P16050 2/20 0.37
KDM4E B2RXH2 1/20 0.37
MAPT P10636 1/20 0.37
ALDH1A1 P00352 2/20 0.37
POLB P06746 1/20 0.37
LMNA P02545 1/20 0.36
HSD17B10 Q99714 1/20 0.36
ATM Q13315 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7369559 0.96 SMN1; SMN2 (0.42) SMN1; SMN2MEN1KMT2AOPRM1OPRD1
SCHEMBL9806691 0.94 SMN1; SMN2 (0.41) SMN1; SMN2MEN1KMT2AOPRM1OPRD1
SCHEMBL670857 0.94 SMN1; SMN2 (0.41) SMN1; SMN2MEN1KMT2AOPRM1OPRD1
SCHEMBL10850510 0.94 SMN1; SMN2 (0.41) SMN1; SMN2MEN1KMT2AOPRM1OPRD1
SCHEMBL3683207 0.92 SMN1; SMN2 (0.41) SMN1; SMN2MEN1KMT2AOPRM1OPRD1
SCHEMBL374081 0.91 OPRM1 (0.41) SMN1; SMN2MEN1KMT2AOPRM1OPRD1
SCHEMBL713102 0.89 SMN1; SMN2 (0.46) SMN1; SMN2MEN1KMT2AOPRM1OPRD1
SCHEMBL1152835 0.85 SMN1; SMN2 (0.42) SMN1; SMN2MEN1KMT2AOPRM1OPRD1
SCHEMBL16086404 0.84 TSHR (0.37) SMN1; SMN2MEN1KMT2AKCNH2ALDH1A1
SCHEMBL5787834 0.83 SMN1; SMN2 (0.42) SMN1; SMN2MEN1KMT2AOPRM1OPRD1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 182 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260049093-A1 Bicyclic Ureas As Kinase Inhibitors INCYTE CORP (US) 2026-02-19 US disclosed
EP-4648799-A1 LIGAND-DRUG CONJUGATES Sun Pharma Advanced Research Company Ltd (IN) 2025-11-19 EP disclosed
US-20250340528-A1 TARGETED PROTEIN DEGRADATION MONTE ROSA THERAPEUTICS AG (CH) 2025-11-06 US disclosed
US-12459920-B2 Targeted protein degradation MONTE ROSA THERAPEUTICS AG (CH) 2025-11-04 US disclosed
EP-4637833-A2 CEREBLON DEGRADER CONJUGATES, AND USES THEREOF Genentech, Inc. (US) 2025-10-29 EP disclosed
US-20250243180-A1 TARGETED PROTEIN DEGRADATION MONTE ROSA THERAPEUTICS AG (CH) 2025-07-31 US disclosed
EP-4588934-A2 BICYCLIC PEPTIDE LIGANDS SPECIFIC FOR NECTIN-4 BicycleTX Limited (GB) 2025-07-23 EP disclosed
CN-120157682-A Deuterated heterocyclic compounds as PDE4B inhibitors and uses thereof 武汉人福创新药物研发中心有限公司 2025-06-17 CN disclosed
CN-116354923-B Nitrogen-containing heterocyclic compound and application thereof 江苏恩华药业股份有限公司 2025-05-09 CN disclosed
US-20250135059-A1 COMPOSITIONS COMPRISING FRAGRANCE MATERIALS THE PROCTER & GAMBLE COMPANY 2025-05-01 US disclosed
EP-0807630-A1 HETEROCYCLIC COMPOUNDS DAIICHI PHARMACEUTICAL CO., LTD. (JP) 1997-11-19 EP disclosed
EP-0806418-A2 Novel pyrimidine compound and anti-rotavirus agent NIPPON SHOJI KAISHA, LIMITED (JP) 1997-11-12 EP disclosed
US-5587386-A BACTERICIDES, MICROBIOCIDES DAIICHI PHARMACEUTICAL CO., LTD. (JP) 1996-12-24 US disclosed
EP-0640594-A1 Hydantoin derivative as metalloprotease inhibitor FUJIREBIO INC. (JP) 1995-03-01 EP disclosed
EP-0275559-B1 PLATINUM CYTOSTATIC AGENT LACHEMA, n.p. (CS) 1991-06-26 EP disclosed
US-4876279-A Antihypercholesterolemic compounds MERCK & CO., INC. (US) 1989-10-24 US disclosed
US-4766145-A Antihypercholesterolemic compounds MERCK & CO., INC. (US) 1988-08-23 US disclosed
EP-0275559-A1 Platinum cytostatic agent LACHEMA, n.p. (CS) 1988-07-27 EP disclosed
CN-87103552-A Adopt malonate derivative to improve crop yield 1988-07-06 CN disclosed
EP-0245004-A2 Antihypercholesterolemic compounds MERCK & CO. INC. (US) 1987-11-11 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260049093-A1 Bicyclic Ureas As Kinase Inhibitors OXSR1, JAK1, NCOR1 SMN1; SMN2 1686/4885MEN1 2881/4885KMT2A 2359/4885
US-20250243180-A1 TARGETED PROTEIN DEGRADATION NEK7, NEK1, RIPK1 SMN1; SMN2 782/4885MEN1 2259/4885KMT2A 3318/4885
US-12459920-B2 Targeted protein degradation NEK7, NEK1, RIPK1 SMN1; SMN2 787/4885MEN1 2268/4885KMT2A 3301/4885
US-20250340528-A1 TARGETED PROTEIN DEGRADATION NEK7, NEK1, RIPK1 SMN1; SMN2 782/4885MEN1 2259/4885KMT2A 3318/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.