SCHEMBL374081

SCHEMBL374081

CCOC(=O)C1(C(=O)O)CC1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
OPRM1 P35372 6/20 0.41
SMN1; SMN2 Q16637 1/20 0.41
OPRD1 P41143 3/20 0.40
OPRK1 P41145 3/20 0.40
ALDH1A1 P00352 2/20 0.40
SLC22A1 O15245 1/20 0.40
SLC6A4 P31645 1/20 0.40
ADRA1A P35348 1/20 0.40
KCNH2 Q12809 1/20 0.40
ALOX15 P16050 2/20 0.39
MEN1 O00255 2/20 0.39
KMT2A Q03164 2/20 0.39
KDM4E B2RXH2 1/20 0.39
MAPT P10636 1/20 0.39
POLB P06746 1/20 0.39
LMNA P02545 1/20 0.39
HSD17B10 Q99714 1/20 0.39
MGAM O43451 1/20 0.37
GAA P10253 1/20 0.37
SI P14410 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7369559 0.91 SMN1; SMN2 (0.42) OPRM1SMN1; SMN2OPRD1OPRK1ALDH1A1
SCHEMBL1654017 0.91 SMN1; SMN2 (0.46) OPRM1SMN1; SMN2OPRD1OPRK1ALDH1A1
SCHEMBL670857 0.90 SMN1; SMN2 (0.41) OPRM1SMN1; SMN2OPRD1OPRK1ALDH1A1
SCHEMBL9806691 0.90 SMN1; SMN2 (0.41) OPRM1SMN1; SMN2OPRD1OPRK1ALDH1A1
SCHEMBL10850510 0.90 SMN1; SMN2 (0.41) OPRM1SMN1; SMN2OPRD1OPRK1ALDH1A1
SCHEMBL18134201 0.88 ALDH1A1 (0.46) OPRM1SMN1; SMN2OPRD1OPRK1ALDH1A1
SCHEMBL69496 0.88 ALDH1A1 (0.46) OPRM1SMN1; SMN2OPRD1OPRK1ALDH1A1
SCHEMBL3683207 0.88 SMN1; SMN2 (0.41) OPRM1SMN1; SMN2OPRD1OPRK1ALDH1A1
SCHEMBL1488529 0.86 OPRM1 (0.54) OPRM1SMN1; SMN2OPRD1OPRK1SLC22A1
SCHEMBL5363175 0.86 TSHR (0.42) OPRM1SMN1; SMN2OPRD1OPRK1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 300 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109311907-A Preparation method of high-purity prasugrel 吉瑞工厂 2019-02-05 CN claimed
CN-105218445-B A kind of preparation method of tyrosine kinase inhibitor Foretinib 江苏中邦制药有限公司 2018-05-22 CN claimed
CN-106316845-A Preparing method of cis, trans-ethyl 2, 2-dimethyl-3-(1-isobutenyl)cyclopropane-1-carboxylate 江苏优普生物化学科技股份有限公司 2017-01-11 CN claimed
CN-106121365-A A kind of Multifunctional household intelligent safety lock and method of work thereof 王公民 2016-11-16 CN claimed
CN-105385202-A Waterproof agent for swimming pool YANTAI SHUNLONG CHEMICAL TECH CO LTD 2016-03-09 CN claimed
CN-105218445-A The preparation method of a kind of TYR enzyme inhibitors Foretinib JIANGSU ZHONGBANG PHARMACEUTICAL CO LTD 2016-01-06 CN claimed
CN-105219536-A A kind of nickel contamination waste material of buildings washing composition YANTAI SHUNLONG CHEMICAL TECHNOLOGY CO LTD 2016-01-06 CN claimed
EP-2603098-B1 METHOD OF IMPROVING STABILITY OF SWEET ENHANCER AND COMPOSITION CONTAINING STABILIZED SWEET ENHANCER FIRMENICH INCORPORATED (US) 2025-08-06 EP disclosed
CN-120192324-A Heterocyclic compound, pharmaceutical composition and application 上海医药集团股份有限公司 2025-06-24 CN disclosed
CN-116178154-B Preparation method of fullerene ester derivative 湖北大学 2025-04-11 CN disclosed
CN-119613408-A Bicyclic ketone compounds and methods of use thereof 豪夫迈·罗氏有限公司 2025-03-14 CN disclosed
CN-110914271-B Bicyclic ketone compounds and methods of use thereof 豪夫迈·罗氏有限公司 2024-12-10 CN disclosed
CN-112390749-B Synthetic method of cabozitinib and intermediate thereof 鲁南制药集团股份有限公司 2024-12-03 CN disclosed
US-5123951-A Ethylene response inducing agent and malonic acid derivative RHONE-POULENC NEDERLAND B.V. (NL) 1992-06-23 US disclosed
EP-0207420-B1 PYRIDONECARBOXYLIC ACID DERIVATIVES DAIICHI PHARMACEUTICAL CO., LTD. (JP) 1992-05-06 EP disclosed
US-5098912-A Bactericides for grampositive bacteria DAIICHI SEIYAKU CO., LTD. (JP) 1992-03-24 US disclosed
US-4876279-A Antihypercholesterolemic compounds MERCK & CO., INC. (US) 1989-10-24 US disclosed
US-4766145-A Antihypercholesterolemic compounds MERCK & CO., INC. (US) 1988-08-23 US disclosed
EP-0245004-A2 Antihypercholesterolemic compounds MERCK & CO. INC. (US) 1987-11-11 EP disclosed
EP-0207420-A2 Pyridonecarboxylic acid derivatives DAIICHI PHARMACEUTICAL CO., LTD. (JP) 1987-01-07 EP disclosed