Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 9/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.58 |
| ▸ | HPGD | P15428 | 2/20 | 0.58 |
| ▸ | MEN1 | O00255 | 1/20 | 0.58 |
| ▸ | NPC1 | O15118 | 1/20 | 0.58 |
| ▸ | RAB9A | P51151 | 1/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.58 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.58 |
| ▸ | RXFP1 | Q9HBX9 | 3/20 | 0.55 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.54 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.54 |
| ▸ | TP53 | P04637 | 3/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | PLK1 | P53350 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16541126 | 0.90 | MAPT (0.61) | MAPTKDM4EALDH1A1HPGDMEN1 | |
| SCHEMBL16540839 | 0.90 | PLK1 (0.52) | MAPTKDM4EALDH1A1HPGDNPC1 | |
| SCHEMBL16540824 | 0.88 | MAPT (0.53) | MAPTKDM4EALDH1A1HPGDNPC1 | |
| SCHEMBL16541083 | 0.81 | MCL1 (0.46) | MAPTKDM4EALDH1A1HPGDNPC1 | |
| SCHEMBL16540606 | 0.80 | KDM4E (0.53) | MAPTKDM4EALDH1A1HPGDMEN1 | |
| SCHEMBL16540846 | 0.79 | KDM4E (0.43) | MAPTKDM4EALDH1A1HPGDMEN1 | |
| SCHEMBL16540897 | 0.79 | MAPK1 (0.56) | MAPTKDM4EALDH1A1HPGDMEN1 | |
| SCHEMBL16540808 | 0.77 | MAPT (0.49) | MAPTKDM4EALDH1A1HPGDNPC1 | |
| SCHEMBL11823964 | 0.77 | MAPT (0.73) | MAPTKDM4EALDH1A1HPGDMEN1 | |
| SCHEMBL18012114 | 0.77 | MAPT (0.59) | MAPTKDM4EALDH1A1HPGDMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9890132-B2 | Process for the preparation of anti-inflammatory aroylbenzofuran compounds | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2018-02-13 | — | — | US | claimed |
| US-20160229827-A1 | A PROCESS FOR THE PREPARATION OF ANTI-INFLAMMATORY AROYLBENZOFURAN COMPOUNDS | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2016-08-11 | — | — | US | claimed |
| WO-2015029062-A1 | A PROCESS FOR THE PREPARATION OF ANTI-INFLAMMATORY AROYLBENZOFURAN COMPOUNDS | COUNCIL OF SCIENTIFIC AND INDUSTRIAL RSEARCH (IN) | 2015-03-05 | — | — | WO | claimed |
| US-9890132-B2 | Process for the preparation of anti-inflammatory aroylbenzofuran compounds | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2018-02-13 | — | — | US | disclosed |
| US-9890132-B2 | Process for the preparation of anti-inflammatory aroylbenzofuran compounds | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2018-02-13 | — | — | US | disclosed |
| US-9890132-B2 | Process for the preparation of anti-inflammatory aroylbenzofuran compounds | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2018-02-13 | — | — | US | disclosed |
| US-20160229827-A1 | A PROCESS FOR THE PREPARATION OF ANTI-INFLAMMATORY AROYLBENZOFURAN COMPOUNDS | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2016-08-11 | — | — | US | disclosed |
| US-20160229827-A1 | A PROCESS FOR THE PREPARATION OF ANTI-INFLAMMATORY AROYLBENZOFURAN COMPOUNDS | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2016-08-11 | — | — | US | disclosed |
| US-20160229827-A1 | A PROCESS FOR THE PREPARATION OF ANTI-INFLAMMATORY AROYLBENZOFURAN COMPOUNDS | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2016-08-11 | — | — | US | disclosed |
| WO-2015029062-A1 | A PROCESS FOR THE PREPARATION OF ANTI-INFLAMMATORY AROYLBENZOFURAN COMPOUNDS | COUNCIL OF SCIENTIFIC AND INDUSTRIAL RSEARCH (IN) | 2015-03-05 | — | — | WO | disclosed |
| WO-2015029062-A1 | A PROCESS FOR THE PREPARATION OF ANTI-INFLAMMATORY AROYLBENZOFURAN COMPOUNDS | COUNCIL OF SCIENTIFIC AND INDUSTRIAL RSEARCH (IN) | 2015-03-05 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160229827-A1 | A PROCESS FOR THE PREPARATION OF ANTI-INFLAMMATORY AROYLBENZOFURAN COMPOUNDS | LITAF, IL1B, CYP2F1 | MAPT 4537/4885KDM4E 2789/4885ALDH1A1 253/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.