Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | APP | P05067 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.44 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | F7 | P08709 | 1/20 | 0.42 |
| ▸ | F3 | P13726 | 1/20 | 0.42 |
| ▸ | SARM1 | Q6SZW1 | 1/20 | 0.42 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.42 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.42 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12158713 | 0.77 | ALDH1A1 (0.53) | HTTALDH1A1APPGAAHCAR3 | |
| SCHEMBL5069202 | 0.76 | PLOD2 (0.48) | HTTALDH1A1APPGAAHCAR3 | |
| SCHEMBL8698366 | 0.75 | HTT (0.51) | HTTALDH1A1APPGAAHCAR3 | |
| SCHEMBL13845395 | 0.75 | ALDH1A1 (0.52) | HTTALDH1A1APPGAAHCAR3 | |
| SCHEMBL18106041 | 0.75 | PLOD2 (0.47) | HTTALDH1A1APPGAAHCAR3 | |
| SCHEMBL2820809 | 0.74 | ALDH1A1 (0.50) | HTTALDH1A1APPGAAHCAR3 | |
| SCHEMBL5162022 | 0.74 | ALDH1A1 (0.55) | HTTALDH1A1APPGAAHCAR3 | |
| SCHEMBL9467060 | 0.74 | ALDH1A1 (0.50) | HTTALDH1A1APPGAAHCAR3 | |
| SCHEMBL27601968 | 0.74 | F7 (0.53) | HTTALDH1A1APPGAAHCAR3 | |
| SCHEMBL5068606 | 0.74 | ALDH1A1 (0.41) | HTTALDH1A1APPGAAHCAR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1408780-A2 | METHOD AND PRODUCT FOR REMOVING CARCINOGENS FROM TOBACCO SMOKE | Vector Tobacco Ltd. (BM) | 2004-04-21 | — | — | EP | claimed |
| WO-2002037990-A2 | METHOD AND PRODUCT FOR REMOVING CARCINOGENS FROM TOBACCO SMOKE | VECTOR TOBACCO LTD. (BM) | 2002-05-16 | — | — | WO | claimed |
| EP-2950674-B1 | IMPROVED AEROSOL FROM TOBACCO | PHILIP MORRIS PRODUCTS SA (CH) | 2023-08-30 | — | — | EP | disclosed |
| EP-3830276-A2 | METHOD FOR REDUCING THE CONTENT OF NITROSAMINE IN TOBACCO USING A CONSTITUTIVELY HIGH AFFINITY CATION EFFLUX TRANSPORTER | British American Tobacco (Investments) Limited (GB) | 2021-06-09 | — | — | EP | disclosed |
| US-10916350-B2 | Systems and methods for quantifying the impact of biological perturbations | PHILIP MORRIS PRODUCTS S.A. (CH) | 2021-02-09 | — | — | US | disclosed |
| CN-112137158-A | Protein-enriched tobacco-derived compositions | R.J.雷诺兹烟草公司 | 2020-12-29 | — | — | CN | disclosed |
| US-20200363401-A1 | Microfluidic Devices and Methods for Use Thereof in Multicellular Assays of Secretion | THE UNIVERSITY OF BRITISH COLUMBIA (CA) | 2020-11-19 | — | — | US | disclosed |
| WO-2020025963-A2 | METHOD | BRITISH AMERICAN TOBACCO (INVESTMENTS) LIMITED (GB) | 2020-02-06 | — | — | WO | disclosed |
| US-10449224-B2 | Flaxseed lignan complex, methods of using and compositions thereof | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) | 2019-10-22 | — | — | US | disclosed |
| US-20170235914-A1 | SYSTEMS AND METHODS FOR QUANTIFYING THE IMPACT OF BIOLOGICAL PERTURBATIONS | PHILIP MORRIS PRODUCTS S.A. (CH) | 2017-08-17 | — | — | US | disclosed |
| CN-103479791-A | Composition for counteracting smoking toxicity | NAM JONG-HYUN | 2014-01-01 | — | — | CN | disclosed |
| CN-103478833-A | Composition for counteracting smoking toxicity | NAM JONG-HYUN | 2014-01-01 | — | — | CN | disclosed |
| US-8609708-B2 | Synthetic compounds and derivatives as modulators of smoking or nicotine ingestion and lung cancer | HUMAN BIOMOLECULAR RESEARCH INSTITUTE (US) | 2013-12-17 | — | — | US | disclosed |
| EP-2611824-A2 | HEAVY METAL REDUCTION IN PLANTA | Philip Morris Products S.A. (CH) | 2013-07-10 | — | — | EP | disclosed |
| CN-102596213-A | Composition for relieving tobacco toxicity | HYUN NAM JONG | 2012-07-18 | — | — | CN | disclosed |
| WO-2012028309-A2 | HEAVY METAL REDUCTION IN PLANTA | PHILIP MORRIS PRODUCTS S.A. (CH) | 2012-03-08 | — | — | WO | disclosed |
| US-20100298345-A1 | SYNTHETIC COMPOUNDS AND DERIVATIVES AS MODULATORS OF SMOKING OR NICOTINE INGESTION AND LUNG CANCER | HUMAN BIOMOLECULAR RESEARCH INSTITUTE (US) | 2010-11-25 | — | — | US | disclosed |
| US-20100239696-A1 | FLAXSEED LIGNAN COMPLEX, METHODS OF USING AMD COMPOSITIONS THEREOF | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) | 2010-09-23 | — | — | US | disclosed |
| EP-1392133-A2 | FUNCTIONAL AGENT FOR DECOMPOSING NICOTINE AND METHOD OF PREPARING THE SAME | Jung, Jong-Moon (KR) | 2004-03-03 | — | — | EP | disclosed |
| WO-2002065978-A2 | FUNCTIONAL AGENT FOR DECOMPOSING NICOTINE AND METHOD OF PREPARING THE SAME | REGEN BIOTECH, INC. (KR) | 2002-08-29 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100298345-A1 | SYNTHETIC COMPOUNDS AND DERIVATIVES AS MODULATORS OF SMOKING OR NICOTINE INGESTION AND LUNG CANCER | CYP2A13, CYP2A6, CYP2B6 | HTT 2271/4885ALDH1A1 762/4885APP 1845/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.