Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.51 |
| ▸ | NPC1 | O15118 | 2/20 | 0.51 |
| ▸ | RAB9A | P51151 | 2/20 | 0.51 |
| ▸ | MAPT | P10636 | 2/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | ATM | Q13315 | 1/20 | 0.51 |
| ▸ | PKM | P14618 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | APP | P05067 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.45 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | F7 | P08709 | 1/20 | 0.44 |
| ▸ | F3 | P13726 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12158713 | 0.88 | ALDH1A1 (0.53) | HTTNPC1RAB9APKMKMT2A | |
| SCHEMBL24588508 | 0.82 | KMT2A (0.51) | HTTNPC1RAB9APKMKMT2A | |
| SCHEMBL10445446 | 0.82 | L3MBTL1 (0.49) | HTTNPC1RAB9APKMKMT2A | |
| SCHEMBL14077805 | 0.78 | L3MBTL1 (0.51) | HTTNPC1RAB9AKMT2AALDH1A1 | |
| SCHEMBL13845395 | 0.76 | ALDH1A1 (0.52) | HTTNPC1RAB9AKMT2AALDH1A1 | |
| SCHEMBL165418 | 0.75 | HTT (0.45) | HTTNPC1RAB9AMAPTPKM | |
| SCHEMBL9467060 | 0.75 | ALDH1A1 (0.50) | HTTNPC1RAB9APKMKMT2A | |
| SCHEMBL27601968 | 0.75 | F7 (0.53) | HTTNPC1RAB9AKMT2AALDH1A1 | |
| SCHEMBL2820809 | 0.75 | ALDH1A1 (0.50) | HTTNPC1RAB9AKMT2AALDH1A1 | |
| SCHEMBL5162022 | 0.75 | ALDH1A1 (0.55) | HTTNPC1RAB9AKMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1998003478-A1 | NITRONE DERIVATIVES, PROCESSES AND INTERMEDIATES FOR THEIR PREPARATION, AND THEIR USE AS HERBICIDES | RHONE-POULENC AGRICULTURE LTD. (GB) | 1998-01-29 | — | — | WO | disclosed |