Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 5/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 5/20 | 0.41 |
| ▸ | HAO1 | Q9UJM8 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | GFER | P55789 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 4/20 | 0.38 |
| ▸ | TAAR5 | O14804 | 1/20 | 0.37 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16542031 | 0.86 | MAOB (0.43) | TAAR5TAAR1ALDH1A1GAA | |
| SCHEMBL16542028 | 0.83 | MEN1 (0.48) | KMT2ALMNATAAR5TAAR1MEN1 | |
| SCHEMBL16542010 | 0.80 | HTR2A (0.44) | HTR2ASLC6A4HAO1KMT2ALMNA | |
| SCHEMBL15957798 | 0.79 | LTA4H (0.57) | KMT2ALMNATAAR5TAAR1GAA | |
| SCHEMBL15957799 | 0.79 | CA12 (0.48) | KMT2AL3MBTL1TAAR5TAAR1ALDH1A1 | |
| SCHEMBL16542035 | 0.77 | TUBB4A (0.47) | KMT2AALDH1A1GAAMEN1MAPT | |
| SCHEMBL20888466 | 0.76 | KMT2A (0.47) | HTR2ASLC6A4HAO1KMT2ALMNA | |
| SCHEMBL16542015 | 0.75 | MAOB (0.46) | KMT2ATAAR5TAAR1ALDH1A1GAA | |
| SCHEMBL23335051 | 0.74 | KMT2A (0.46) | HTR2ASLC6A4HAO1KMT2ALMNA | |
| SCHEMBL22925956 | 0.73 | TRPA1 (0.48) | HTR2AKMT2ALMNAL3MBTL1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2536726-B1 | DIARYL ETHER LINKED PYRROLO [2,1-C][1,4]BENZODIAZEPINE HYBRIDS AND PROCESS FOR THE PREPARATION THEREOF | COUNCIL SCIENT IND RES (IN) | 2015-03-04 | — | — | EP | disclosed |