Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 6/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 5/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 8/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 8/20 | 0.38 |
| ▸ | SLC6A3 | Q01959 | 7/20 | 0.37 |
| ▸ | LMNA | P02545 | 3/20 | 0.36 |
| ▸ | NPY1R | P25929 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | NPY2R | P49146 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16544651 | 0.95 | PDK2 (0.41) | CYP1A2ALDH1A1CYP2D6CYP3A4KDM4E | |
| SCHEMBL16544649 | 0.93 | PDK2 (0.42) | CYP1A2ALDH1A1CYP2D6CYP3A4KDM4E | |
| SCHEMBL16544644 | 0.86 | CYP1A2 (0.43) | CYP1A2ALDH1A1CYP2D6CYP3A4KDM4E | |
| SCHEMBL16544648 | 0.84 | CYP1A2 (0.42) | CYP1A2ALDH1A1CYP2D6CYP3A4KDM4E | |
| SCHEMBL16544656 | 0.84 | CYP1A2 (0.42) | CYP1A2ALDH1A1CYP2D6CYP3A4KDM4E | |
| SCHEMBL16544769 | 0.84 | GABRA1 (0.40) | CYP1A2ALDH1A1CYP2D6CYP3A4KDM4E | |
| SCHEMBL19735235 | 0.80 | LMNA (0.37) | CYP1A2ALDH1A1CYP2D6CYP3A4KDM4E | |
| SCHEMBL18079825 | 0.79 | ADORA2A (0.42) | CYP1A2ALDH1A1CYP2D6KDM4EHPGD | |
| SCHEMBL15892355 | 0.77 | PDK2 (0.36) | ALDH1A1MAPK1TSHRMAPTHSD17B10 | |
| SCHEMBL18079822 | 0.77 | PDK2 (0.43) | CYP1A2ALDH1A1CYP2D6KDM4EHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180019405-A1 | MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES | MERCK PATENT GMBH (DE) | 2018-01-18 | — | — | US | disclosed |
| US-9812648-B2 | Spirobifluorene compounds for organic electroluminescent devices | MERCK PATENT GMBH (DE) | 2017-11-07 | — | — | US | disclosed |
| US-20150065730-A1 | SPIROBIFLUORENE COMPOUNDS FOR ORGANIC ELECTROLUMINESCENT DEVICES | MERCK PATENT GMBH (DE) | 2015-03-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180019405-A1 | MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES | L1CAM, EFNA1, EPCAM | CYP1A2 390/4885ALDH1A1 33/4885CYP2D6 448/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.