SCHEMBL165468

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL167899	0.91	MET (0.54)	LRRK2METPTGER1RXFP1KCNH2
	SCHEMBL168123	0.88	LRRK2 (0.60)	LRRK2METPTGER1HTTRECQL
	SCHEMBL167994	0.86	LRRK2 (0.60)	LRRK2METCYP3A4SLCO1B1
	SCHEMBL257184	0.85	LRRK2 (0.64)	LRRK2KCNH2CYP3A4SLCO1B1
	SCHEMBL167180	0.83	PTGER1 (0.45)	PTGER1HTTRECQLSMN1; SMN2TP53
	SCHEMBL168763	0.82	HCRTR1 (0.46)	PTGER1HTTRECQLKCNH2SMN1; SMN2
	SCHEMBL168574	0.82	MET (0.51)	LRRK2METPTGER1HTTRECQL
	SCHEMBL257054	0.78	LRRK2 (0.58)	LRRK2METHTTNPC1RAB9A
	SCHEMBL256458	0.78	LRRK2 (0.62)	LRRK2MET
	SCHEMBL257191	0.76	LRRK2 (0.63)	LRRK2KCNH2CYP3A4SLCO1B1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.