Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | RPS6KB2 | Q9UBS0 | 1/20 | 0.41 |
| ▸ | EGFR | P00533 | 2/20 | 0.34 |
| ▸ | PDGFRB | P09619 | 2/20 | 0.34 |
| ▸ | PDGFRA | P16234 | 2/20 | 0.34 |
| ▸ | SNCA | P37840 | 1/20 | 0.34 |
| ▸ | PGK1 | P00558 | 1/20 | 0.34 |
| ▸ | NQO1 | P15559 | 1/20 | 0.33 |
| ▸ | MYC | P01106 | 1/20 | 0.33 |
| ▸ | MAX | P61244 | 1/20 | 0.33 |
| ▸ | NQO2 | P16083 | 1/20 | 0.32 |
| ▸ | ACHE | P22303 | 1/20 | 0.32 |
| ▸ | APP | P05067 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | STAT3 | P40763 | 1/20 | 0.31 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.30 |
| ▸ | SRC | P12931 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9979780 | 0.86 | MAPT (0.46) | KDM4EMAPTRPS6KB2EGFRPDGFRB | |
| SCHEMBL9979784 | 0.86 | NQO1 (0.44) | KDM4EMAPTRPS6KB2NQO1NQO2 | |
| SCHEMBL9979793 | 0.81 | NQO1 (0.36) | KDM4EMAPTRPS6KB2PGK1NQO1 | |
| SCHEMBL11995959 | 0.80 | ACHE (0.43) | KDM4EMAPTRPS6KB2EGFRPDGFRB | |
| SCHEMBL9979789 | 0.79 | EGFR (0.36) | KDM4EMAPTRPS6KB2EGFRPDGFRB | |
| SCHEMBL1259502 | 0.75 | KDM4E (0.64) | KDM4EMAPTPDGFRBNQO2ALDH1A1 | |
| 2,3-Dihydroxy-6,7-Dichloroquinoxaline SCHEMBL1259521 | 0.75 | MMP1 (0.50) | PGK1NQO2ALDH1A1GAAHPGD | |
| SCHEMBL10348834 | 0.75 | MAPT (0.52) | KDM4EMAPTNQO1ALDH1A1GAA | |
| SCHEMBL4705252 | 0.75 | PIK3R1 (0.39) | KDM4EMAPTNQO1NQO2ALDH1A1 | |
| SCHEMBL10846210 | 0.75 | KDM4E (0.38) | KDM4EMAPTNQO1ALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10273339-B2 | Synthesis of a highly crystalline, covalently linked porous network | UNIVERSITY OF SOUTH CAROLINA (US) | 2019-04-30 | — | — | US | disclosed |
| US-20150065596-A1 | Synthesis of a Highly Crystalline, Covalently Linked Porous Network | UNIVERSITY OF SOUTH CAROLINA | 2015-03-05 | — | — | US | disclosed |
| US-20150065596-A1 | Synthesis of a Highly Crystalline, Covalently Linked Porous Network | UNIVERSITY OF SOUTH CAROLINA | 2015-03-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10273339-B2 | Synthesis of a highly crystalline, covalently linked porous network | PARN, PARG, PUF60 | KDM4E 3135/4885MAPT 628/4885RPS6KB2 1417/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.