Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | PTGES | O14684 | 8/20 | 0.38 |
| ▸ | P2RX7 | Q99572 | 4/20 | 0.38 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | CNR2 | P34972 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16665063 | 0.91 | P2RX7 (0.38) | LMNAGAAP2RX7CHRM3TP53 | |
| SCHEMBL16665046 | 0.90 | LMNA (0.41) | LMNAGAAPTGESP2RX7CHRM3 | |
| SCHEMBL18503625 | 0.89 | CHRM3 (0.40) | LMNAGAAPTGESP2RX7CHRM3 | |
| SCHEMBL16665050 | 0.89 | GRIN2B (0.43) | P2RX7TP53 | |
| SCHEMBL16665036 | 0.89 | TP53 (0.45) | LMNAGAAP2RX7TP53CNR2 | |
| SCHEMBL17991472 | 0.89 | P2RX7 (0.41) | LMNAGAAPTGESP2RX7TP53 | |
| SCHEMBL16665066 | 0.88 | HIF1A (0.40) | LMNAGAAP2RX7POLBHPGD | |
| SCHEMBL17917768 | 0.88 | P2RX7 (0.39) | LMNAGAAPTGESP2RX7TP53 | |
| SCHEMBL16654673 | 0.88 | P2RX7 (0.44) | LMNAGAAP2RX7KDM4ECNR2 | |
| SCHEMBL16665062 | 0.88 | P2RX7 (0.40) | LMNAGAAPTGESP2RX7KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3039018-B1 | PYRIDYL CARBOXAMIDE DERIVATIVES WITH PESTICIDAL ACTIVITY | BAYER CROPSCIENCE AG (DE) | 2017-08-02 | — | — | EP | disclosed |
| WO-2015028427-A1 | COMPOUNDS WITH PESTICIDAL ACTIVITY | BAYER CROPSCIENCE AG (DE) | 2015-03-05 | — | — | WO | disclosed |