Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX7 | Q99572 | 6/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | GRIN2B | Q13224 | 6/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.36 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16665050 | 0.94 | GRIN2B (0.43) | P2RX7TP53GRIN2B | |
| SCHEMBL16552201 | 0.91 | LMNA (0.38) | P2RX7TP53LMNAKDM4EGAA | |
| SCHEMBL16654673 | 0.91 | P2RX7 (0.44) | P2RX7LMNAKDM4EGAAALDH1A1 | |
| SCHEMBL16665036 | 0.90 | TP53 (0.45) | P2RX7TP53LMNAGAACHRNA7 | |
| SCHEMBL16552225 | 0.90 | GRM4 (0.38) | P2RX7TP53LMNAGAAALDH1A1 | |
| SCHEMBL17991469 | 0.89 | ALDH1A1 (0.43) | P2RX7LMNAKDM4EGAAALDH1A1 | |
| SCHEMBL17917768 | 0.89 | P2RX7 (0.39) | P2RX7TP53LMNAKDM4EGAA | |
| SCHEMBL16665062 | 0.89 | P2RX7 (0.40) | P2RX7LMNAKDM4EGAAALDH1A1 | |
| SCHEMBL16665046 | 0.89 | LMNA (0.41) | P2RX7LMNAKDM4EGAACHRM3 | |
| SCHEMBL16552193 | 0.88 | DGAT1 (0.41) | P2RX7TP53LMNAKDM4EGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9776967-B2 | Carboxamide derivatives as pesticidal compounds | BAYER ANIMAL HEALTH GMBH (DE) | 2017-10-03 | — | — | US | disclosed |
| US-9776967-B2 | Carboxamide derivatives as pesticidal compounds | BAYER ANIMAL HEALTH GMBH (DE) | 2017-10-03 | — | — | US | disclosed |
| US-20160221950-A1 | CARBOXAMIDE DERIVATIVES AS PESTICIDAL COMPOUNDS | ELANCO ANIMAL HEALTH GMBH (DE) | 2016-08-04 | — | — | US | disclosed |
| US-20160221950-A1 | CARBOXAMIDE DERIVATIVES AS PESTICIDAL COMPOUNDS | ELANCO ANIMAL HEALTH GMBH (DE) | 2016-08-04 | — | — | US | disclosed |
| WO-2015055535-A1 | CARBOXAMIDE DERIVATIVES AS PESTICIDAL COMPOUNDS | BAYER CROPSCIENCE AG (DE) | 2015-04-23 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160221950-A1 | CARBOXAMIDE DERIVATIVES AS PESTICIDAL COMPOUNDS | ACHE, DDT, NIT2 | P2RX7 323/4885TP53 4879/4885GRIN2B 391/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.