Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.32 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.32 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.32 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.32 |
| ▸ | STAT6 | P42226 | 1/20 | 0.32 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.32 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.32 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.32 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.32 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.32 |
| ▸ | SLC47A1 | Q96FL8 | 1/20 | 0.32 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | THRB | P10828 | 1/20 | 0.31 |
| ▸ | BLM | P54132 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3843092 | 0.74 | GRIN2D (0.35) | LMNASLC22A2SLC22A1GRIN2DGRIN3B | |
| SCHEMBL546127 | 0.72 | CYP2C9 (0.39) | LMNASLC22A2SLC22A1GRIN2DGRIN3B | |
| SCHEMBL25338011 | 0.70 | GRIN2D (0.38) | LMNASLC22A2SLC22A1GRIN2DGRIN3B | |
| SCHEMBL4329163 | 0.70 | LMNA (0.32) | LMNASLC22A2SLC22A1GRIN2DGRIN3B | |
| SCHEMBL1015951 | 0.70 | GRIN2D (0.38) | LMNASLC22A2SLC22A1GRIN2DGRIN3B | |
| SCHEMBL678264 | 0.70 | GRIN2D (0.33) | LMNASLC22A2SLC22A1GRIN2DGRIN3B | |
| Hydrochloric Acid SCHEMBL1015666 | 0.68 | LMNA (0.40) | LMNASLC22A2SLC22A1GRIN2DGRIN3B | |
| SCHEMBL10574918 | 0.67 | GRIN2D (0.38) | LMNASLC22A2SLC22A1GRIN2DGRIN3B | |
| SCHEMBL12837488 | 0.67 | EPHX2 (0.32) | GRIN2DGRIN3BGRIN1GRIN2AGRIN2B | |
| SCHEMBL1592795 | 0.67 | GRIN2D (0.31) | GRIN2DGRIN3BGRIN1GRIN2AGRIN2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015035234-A2 | ANTI-MICROBIAL COMPOUNDS AND COMPOSITIONS | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) | 2015-03-12 | — | — | WO | disclosed |