SCHEMBL12837488

SCHEMBL12837488

ON(O)C1C2CC3CC(C2)CC1(O)C3

nearest known ligand 0.32

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
EPHX2 P34913 3/20 0.32
GRIN2D O15399 1/20 0.31
GRIN3B O60391 1/20 0.31
GRIN1 Q05586 1/20 0.31
GRIN2A Q12879 1/20 0.31
GRIN2B Q13224 1/20 0.31
GRIN2C Q14957 1/20 0.31
GRIN3A Q8TCU5 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3843092 0.70 GRIN2D (0.35) EPHX2GRIN2DGRIN3BGRIN1GRIN2A
SCHEMBL546127 0.69 CYP2C9 (0.39) EPHX2GRIN2DGRIN3BGRIN1GRIN2A
SCHEMBL16554143 0.67 LMNA (0.32) EPHX2GRIN2DGRIN3BGRIN1GRIN2A
SCHEMBL4329163 0.67 LMNA (0.32) EPHX2GRIN2DGRIN3BGRIN1GRIN2A
SCHEMBL1015951 0.67 GRIN2D (0.38) EPHX2GRIN2DGRIN3BGRIN1GRIN2A
SCHEMBL25338011 0.67 GRIN2D (0.38) EPHX2GRIN2DGRIN3BGRIN1GRIN2A
SCHEMBL678264 0.67 GRIN2D (0.33) EPHX2GRIN2DGRIN3BGRIN1GRIN2A
Hydrochloric Acid SCHEMBL1015666 0.65 LMNA (0.40) GRIN2DGRIN3BGRIN1GRIN2AGRIN2B
SCHEMBL10574918 0.64 GRIN2D (0.38) EPHX2GRIN2DGRIN3BGRIN1GRIN2A
SCHEMBL1592795 0.64 GRIN2D (0.31) EPHX2GRIN2DGRIN3BGRIN1GRIN2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20110065762-A1 METHODS OF USE OF ANTIVIRAL COMPOUNDS INFLUMEDIX, INC. 2011-03-17 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110065762-A1 METHODS OF USE OF ANTIVIRAL COMPOUNDS MAVS, SLC30A5, HAVCR2 EPHX2 3743/4885GRIN2D 1890/4885GRIN3B 2206/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.