Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACACB | O00763 | 2/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | TAS1R3 | Q7RTX0 | 2/20 | 0.34 |
| ▸ | TAS1R1 | Q7RTX1 | 2/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | CNR2 | P34972 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16554038 | 0.87 | ACACB (0.38) | ACACBHTTALDH1A1LMNACNR2 | |
| SCHEMBL16554170 | 0.84 | ACACB (0.34) | ACACBMAPK1HTTTAS1R3TAS1R1 | |
| SCHEMBL1814307 | 0.77 | ALDH1A1 (0.42) | MAPK1TAS1R3TAS1R1GAAALDH1A1 | |
| SCHEMBL16585783 | 0.77 | TAS1R3 (0.31) | MAPK1TAS1R3TAS1R1ALDH1A1KMT2A | |
| SCHEMBL16554097 | 0.76 | ERN1 (0.38) | MAPK1TAS1R3TAS1R1GAAALDH1A1 | |
| SCHEMBL1152535 | 0.68 | ALDH1A1 (0.41) | TAS1R3TAS1R1GAAALDH1A1HPGD | |
| SCHEMBL8865572 | 0.68 | ALDH1A1 (0.44) | MAPK1GAAALDH1A1HPGDMEN1 | |
| SCHEMBL7486568 | 0.68 | MAPK1 (0.43) | MAPK1HTTTAS1R3TAS1R1ALDH1A1 | |
| SCHEMBL8865914 | 0.68 | ACACB (0.46) | ACACBMAPK1GAAALDH1A1HPGD | |
| SCHEMBL22163450 | 0.67 | ALDH1A1 (0.39) | HTTTAS1R3TAS1R1GAAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015032702-A1 | HERBICIDALLY ACTIVE 2-HALOGEN-4-ALKYNYL- PHENYL-PYRAZOLIDINE-DIONE OR PYRROLIDINE-DIONE DERIVATIVES | SYNGENTA LIMITED (GB) | 2015-03-12 | — | — | WO | disclosed |
| WO-2015032702-A1 | HERBICIDALLY ACTIVE 2-HALOGEN-4-ALKYNYL- PHENYL-PYRAZOLIDINE-DIONE OR PYRROLIDINE-DIONE DERIVATIVES | SYNGENTA LIMITED (GB) | 2015-03-12 | — | — | WO | disclosed |