Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | TAS1R3 | Q7RTX0 | 2/20 | 0.38 |
| ▸ | TAS1R1 | Q7RTX1 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | CNR2 | P34972 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | ERN1 | O75460 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5570549 | 0.86 | KDM4E (0.41) | ALDH1A1GAALMNAKDM4ECNR2 | |
| SCHEMBL12702938 | 0.78 | ERN1 (0.42) | ALDH1A1GAALMNAKDM4ECNR2 | |
| SCHEMBL12658255 | 0.74 | ALDH1A1 (0.44) | ALDH1A1GAALMNAKDM4EMEN1 | |
| SCHEMBL6807015 | 0.74 | TAS1R3 (0.40) | ALDH1A1TAS1R3TAS1R1KDM4ESMN1; SMN2 | |
| SCHEMBL1814307 | 0.73 | ALDH1A1 (0.42) | ALDH1A1GAALMNATAS1R3TAS1R1 | |
| SCHEMBL510312 | 0.72 | KDM4E (0.46) | ALDH1A1GAALMNAKDM4EMEN1 | |
| SCHEMBL12658340 | 0.72 | KDM4E (0.39) | ALDH1A1GAALMNAKDM4ECNR2 | |
| SCHEMBL16554097 | 0.72 | ERN1 (0.38) | ALDH1A1GAATAS1R3TAS1R1MEN1 | |
| SCHEMBL13888758 | 0.72 | ERN1 (0.56) | ALDH1A1GAALMNAKDM4EERN1 | |
| SCHEMBL27515050 | 0.70 | LOXL2 (0.41) | ALDH1A1GAAMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1606254-B1 | 2,4,6-PHENYL SUBSTITUTED CYCLIC KETOENOLS | BAYER CROPSCIENCE AG (DE) | 2011-05-11 | — | — | EP | disclosed |
| US-20110092368-A1 | 2,4,6-Phenyl-substituted cyclic ketoenols | FISCHER REINER | 2011-04-21 | — | — | US | disclosed |
| US-20110092368-A1 | 2,4,6-Phenyl-substituted cyclic ketoenols | FISCHER REINER | 2011-04-21 | — | — | US | disclosed |
| US-20110092368-A1 | 2,4,6-Phenyl-substituted cyclic ketoenols | FISCHER REINER | 2011-04-21 | — | — | US | disclosed |
| US-7888285-B2 | 2,4,6-phenyl substituted cyclic ketoenols | BAYER CROPSCIENCE AG (DE) | 2011-02-15 | — | — | US | disclosed |
| US-7888285-B2 | 2,4,6-phenyl substituted cyclic ketoenols | BAYER CROPSCIENCE AG (DE) | 2011-02-15 | — | — | US | disclosed |
| US-7888285-B2 | 2,4,6-phenyl substituted cyclic ketoenols | BAYER CROPSCIENCE AG (DE) | 2011-02-15 | — | — | US | disclosed |
| US-20070015664-A1 | 2,4,6-Phenyl substituted cyclic ketoenols | BAYER CROPSCIENCE AG (DE) | 2007-01-18 | — | — | US | disclosed |
| US-20070015664-A1 | 2,4,6-Phenyl substituted cyclic ketoenols | BAYER CROPSCIENCE AG (DE) | 2007-01-18 | — | — | US | disclosed |
| EP-1606254-A1 | 2,4,6-PHENYL SUBSTITUTED CYCLIC KETOENOLS | Bayer CropScience AG (DE) | 2005-12-21 | — | — | EP | disclosed |
| WO-2004080962-A1 | 2,4,6-PHENYL SUBSTITUTED CYCLIC KETOENOLS | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2004-09-23 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070015664-A1 | 2,4,6-Phenyl substituted cyclic ketoenols | CYP4X1, KDM4E, KCNE1 | ALDH1A1 2306/4885GAA 1055/4885LMNA 4052/4885 |
| US-20110092368-A1 | 2,4,6-Phenyl-substituted cyclic ketoenols | CYP4X1, KDM4E, PDHX | ALDH1A1 2227/4885GAA 1079/4885LMNA 4209/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.