Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | L3MBTL4 | Q8NA19 | 1/20 | 0.34 |
| ▸ | L3MBTL3 | Q96JM7 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 2/20 | 0.34 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.34 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.33 |
| ▸ | RIPK2 | O43353 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | CYP11B2 | P19099 | 3/20 | 0.33 |
| ▸ | TAS1R3 | Q7RTX0 | 2/20 | 0.31 |
| ▸ | TAS1R1 | Q7RTX1 | 2/20 | 0.31 |
| ▸ | TAS1R2 | Q8TE23 | 2/20 | 0.31 |
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16554216 | 0.85 | NPSR1 (0.35) | NPSR1ALDH1A1OPRL1RIPK2MEN1 | |
| SCHEMBL17940888 | 0.85 | NPSR1 (0.35) | NPSR1ALDH1A1OPRL1RIPK2MEN1 | |
| SCHEMBL17940845 | 0.84 | NPSR1 (0.37) | NPSR1ALDH1A1OPRL1RIPK2MEN1 | |
| SCHEMBL16115082 | 0.83 | CHRM2 (0.39) | RIPK2 | |
| SCHEMBL16116308 | 0.83 | CHRM2 (0.39) | RIPK2 | |
| SCHEMBL17507206 | 0.83 | CHRM2 (0.39) | RIPK2 | |
| SCHEMBL7985946 | 0.83 | RIPK2 (0.32) | NPSR1L3MBTL4L3MBTL3L3MBTL1RIPK2 | |
| SCHEMBL7222900 | 0.82 | OPRL1 (0.36) | OPRL1RIPK2 | |
| SCHEMBL7972022 | 0.81 | RIPK2 (0.32) | L3MBTL4L3MBTL3L3MBTL1OPRL1RIPK2 | |
| SCHEMBL7697916 | 0.80 | OPRL1 (0.40) | ALDH1A1POLBOPRL1RIPK2TAS1R3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160214974-A1 | INSECTICIDAL COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2016-07-28 | — | — | US | disclosed |
| EP-3041833-A1 | INSECTICIDAL COMPOUNDS | Syngenta Participations AG (CH) | 2016-07-13 | — | — | EP | disclosed |
| WO-2015032617-A1 | INSECTICIDAL COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2015-03-12 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160214974-A1 | INSECTICIDAL COMPOUNDS | ACHE, CYP1B1, CHRM1 | NPSR1 696/4885ALDH1A1 78/4885L3MBTL4 1127/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.