Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RIPK2 | O43353 | 1/20 | 0.32 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.32 |
| ▸ | L3MBTL4 | Q8NA19 | 1/20 | 0.30 |
| ▸ | L3MBTL3 | Q96JM7 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7223598 | 0.85 | OPRL1 (0.36) | RIPK2OPRL1 | |
| SCHEMBL7222900 | 0.83 | OPRL1 (0.36) | RIPK2OPRL1 | |
| SCHEMBL7971885 | 0.82 | KMT2A (0.34) | RIPK2OPRL1 | |
| SCHEMBL16554354 | 0.81 | NPSR1 (0.35) | RIPK2OPRL1L3MBTL4L3MBTL3L3MBTL1 | |
| SCHEMBL7699063 | 0.79 | CHRNB2 (0.34) | RIPK2OPRL1 | |
| SCHEMBL16135496 | 0.79 | OPRL1 (0.32) | RIPK2OPRL1 | |
| SCHEMBL16115749 | 0.79 | OPRL1 (0.32) | RIPK2OPRL1 | |
| SCHEMBL16565906 | 0.78 | OPRL1 (0.31) | OPRL1 | |
| SCHEMBL7697916 | 0.78 | OPRL1 (0.40) | RIPK2OPRL1 | |
| SCHEMBL16554204 | 0.78 | OPRL1 (0.31) | OPRL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6294545-B1 | INSECTICIDES | SYNGENTA LIMITED (GB) | 2001-09-25 | — | — | US | disclosed |
| EP-1033914-A1 | BICYCLIC AMINES AND THEIR USE AS INSECTICIDES | ZENECA LIMITED (GB) | 2000-09-13 | — | — | EP | disclosed |
| WO-1999026478-A1 | BICYCLIC AMINES AND THEIR USE AS INSECTICIDES | ZENECA LIMITED (GB) | 1999-06-03 | — | — | WO | disclosed |