Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.55 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.55 |
| ▸ | SRD5A2 | P31213 | 3/20 | 0.53 |
| ▸ | CDH1 | P12830 | 1/20 | 0.51 |
| ▸ | APC | P25054 | 1/20 | 0.51 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.51 |
| ▸ | TCF7L2 | Q9NQB0 | 1/20 | 0.51 |
| ▸ | AURKA | O14965 | 1/20 | 0.51 |
| ▸ | TPX2 | Q9ULW0 | 1/20 | 0.51 |
| ▸ | MAP4K4 | O95819 | 2/20 | 0.50 |
| ▸ | RXRA | P19793 | 1/20 | 0.50 |
| ▸ | RXRB | P28702 | 1/20 | 0.50 |
| ▸ | SRD5A1 | P18405 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | FASN | P49327 | 1/20 | 0.46 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6224208 | 0.88 | RARB (0.56) | TSHRALOX15SRD5A2CDH1APC | |
| SCHEMBL3215926 | 0.86 | KMO (0.52) | MAP4K4KDM4ELMNAHSD17B10BCL2L1 | |
| SCHEMBL16554472 | 0.85 | PTGER1 (0.52) | KMT2AKDM4EPOLBTTR | |
| SCHEMBL2555397 | 0.84 | MAPT (0.48) | RXRARXRBMEN1KMT2AKDM4E | |
| SCHEMBL14273027 | 0.82 | TSHR (0.55) | TSHRALOX15SRD5A2CDH1APC | |
| SCHEMBL2560576 | 0.81 | ALDH1A1 (0.56) | KDM4ELMNAHSD17B10BCL2L1BAD | |
| SCHEMBL6224543 | 0.81 | SRD5A2 (0.64) | TSHRALOX15SRD5A2MAP4K4RXRA | |
| SCHEMBL2744832 | 0.80 | SLC22A12 (0.56) | MAP4K4KDM4ELMNAHSD17B10 | |
| SCHEMBL22442333 | 0.80 | ERN1 (0.52) | TSHRALOX15KDM4ELMNAHSD17B10 | |
| SCHEMBL31038313 | 0.80 | CA1 (0.58) | MAP4K4RXRAMEN1KMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015034271-A1 | NOVEL ANTIFUNGAL PYRIDINYLHYDRAZIDE DERIVATIVES | DAEWOONG PHARMACEUTICAL CO., LTD. (KR) | 2015-03-12 | — | — | WO | disclosed |