SCHEMBL1655544

SCHEMBL1655544

O=C1OC(=O)c2cc(Oc3ccc(-c4ccccc4)cc3)ccc21

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAOA P21397 5/20 0.56
MAOB P27338 5/20 0.56
GSTP1 P09211 2/20 0.53
L3MBTL1 Q9Y468 3/20 0.48
TDP1 Q9NUW8 2/20 0.48
MAPT P10636 2/20 0.48
ALOX15 P16050 1/20 0.43
ACHE P22303 2/20 0.43
NPC1 O15118 2/20 0.43
RAB9A P51151 2/20 0.43
POLB P06746 1/20 0.43
HDAC8 Q9BY41 1/20 0.43
LMNA P02545 2/20 0.42
FFAR1 O14842 1/20 0.41
FFAR4 Q5NUL3 1/20 0.41
MEN1 O00255 1/20 0.41
APAF1 O14727 1/20 0.41
THRB P10828 1/20 0.41
XBP1 P17861 1/20 0.41
PTBP1 P26599 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3625447 0.95 MAOA (0.51) MAOAMAOBGSTP1L3MBTL1TDP1
SCHEMBL10414698 0.91 MAOA (0.66) MAOAMAOBGSTP1L3MBTL1TDP1
SCHEMBL31634592 0.91 MAOA (0.66) MAOAMAOBGSTP1L3MBTL1TDP1
SCHEMBL2828515 0.91 MAOA (0.66) MAOAMAOBGSTP1L3MBTL1TDP1
SCHEMBL84254 0.89 MAOA (0.56) MAOAMAOBGSTP1L3MBTL1TDP1
SCHEMBL1501398 0.89 MAOA (0.56) MAOAMAOBGSTP1L3MBTL1TDP1
SCHEMBL30970619 0.89 MAOA (0.56) MAOAMAOBGSTP1L3MBTL1TDP1
SCHEMBL42261 0.87 MAOA (0.53) MAOAMAOBGSTP1L3MBTL1TDP1
SCHEMBL30950420 0.87 MAOA (0.53) MAOAMAOBGSTP1L3MBTL1TDP1
SCHEMBL3911696 0.86 ALDH1A1 (0.56) MAOAMAOBGSTP1L3MBTL1TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4960905-A CURING AGENT FOR EPOXY RESINS OCCIDENTAL CHEMICAL CORPORATION (US) 1990-10-02 US claimed
EP-0308863-A2 Process for the preparation of phenoxy phthalic anhydrides OCCIDENTAL CHEMICAL CORPORATION (US) 1989-03-29 EP claimed
EP-2032610-B1 METHODS OF PREPARING POLYMER-ORGANOCLAY COMPOSITES AND ARTICLES DERIVED THEREFROM GEN ELECTRIC (US) 2013-07-31 EP disclosed
US-8278383-B2 Methods of preparing polymer-organoclay composites and articles derived therefrom SABIC INNOVATIVE PLASTICS IP B.V. (NL) 2012-10-02 US disclosed
US-8278383-B2 Methods of preparing polymer-organoclay composites and articles derived therefrom SABIC INNOVATIVE PLASTICS IP B.V. (NL) 2012-10-02 US disclosed
US-8278383-B2 Methods of preparing polymer-organoclay composites and articles derived therefrom SABIC INNOVATIVE PLASTICS IP B.V. (NL) 2012-10-02 US disclosed
US-20120190791-A1 METHODS OF PREPARING POLYMER-ORGANOCLAY COMPOSITES AND ARTICLES DERIVED THEREFROM SABIC INNOVATIVE PLASTICS IP BV (NL) 2012-07-26 US disclosed
US-20120190791-A1 METHODS OF PREPARING POLYMER-ORGANOCLAY COMPOSITES AND ARTICLES DERIVED THEREFROM SABIC INNOVATIVE PLASTICS IP BV (NL) 2012-07-26 US disclosed
US-20120190791-A1 METHODS OF PREPARING POLYMER-ORGANOCLAY COMPOSITES AND ARTICLES DERIVED THEREFROM SABIC INNOVATIVE PLASTICS IP BV (NL) 2012-07-26 US disclosed
US-8158243-B2 Methods of preparing polymer-organoclay composites and articles derived therefrom SABIC INNOVATIVE PLASTICS IP B.V. (NL) 2012-04-17 US disclosed
US-8158243-B2 Methods of preparing polymer-organoclay composites and articles derived therefrom SABIC INNOVATIVE PLASTICS IP B.V. (NL) 2012-04-17 US disclosed
US-7928154-B2 Methods of preparing polymer-organoclay composites and articles derived therefrom SABIC INNOVATIVE PLASTICS IP B.V. (NL) 2011-04-19 US disclosed
EP-2032610-A2 METHODS OF PREPARING POLYMER-ORGANOCLAY COMPOSITES AND ARTICLES DERIVED THEREFROM GENERAL ELECTRIC COMPANY (US) 2009-03-11 EP disclosed
US-20080004391-A1 METHODS OF PREPARING POLYMER-ORGANOCLAY COMPOSITES AND ARTICLES DERIVED THEREFROM SABIC INNOVATIVE PLASTICS IP B.V. (NL) 2008-01-03 US disclosed
US-20080004391-A1 METHODS OF PREPARING POLYMER-ORGANOCLAY COMPOSITES AND ARTICLES DERIVED THEREFROM SABIC INNOVATIVE PLASTICS IP B.V. (NL) 2008-01-03 US disclosed
US-20080004391-A1 METHODS OF PREPARING POLYMER-ORGANOCLAY COMPOSITES AND ARTICLES DERIVED THEREFROM SABIC INNOVATIVE PLASTICS IP B.V. (NL) 2008-01-03 US disclosed
WO-2008002870-A2 METHODS OF PREPARING POLYMER-ORGANOCLAY COMPOSITES AND ARTICLES DERIVED THEREFROM SABIC INNOVATIVE PLASTICS IP B.V. (NL) 2008-01-03 WO disclosed
US-4960905-A CURING AGENT FOR EPOXY RESINS OCCIDENTAL CHEMICAL CORPORATION (US) 1990-10-02 US disclosed
US-4827000-A REACTION OF FLUOROPHTHALIC ANHYDRIDE WITH A PHENOL OCCIDENTAL CHEMICAL CORPORATION (US) 1989-05-02 US disclosed
EP-0308863-A2 Process for the preparation of phenoxy phthalic anhydrides OCCIDENTAL CHEMICAL CORPORATION (US) 1989-03-29 EP disclosed