SCHEMBL2828515

SCHEMBL2828515

O=C1OC(=O)c2cc(Oc3ccccc3)ccc21

nearest known ligand 0.66

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
MAOA P21397 5/20 0.66
MAOB P27338 5/20 0.66
L3MBTL1 Q9Y468 2/20 0.55
TDP1 Q9NUW8 2/20 0.55
MAPT P10636 1/20 0.55
GSTP1 P09211 1/20 0.53
ACHE P22303 2/20 0.50
NPC1 O15118 1/20 0.50
POLB P06746 1/20 0.50
RAB9A P51151 1/20 0.50
ALOX15 P16050 1/20 0.48
LTA4H P09960 1/20 0.46
TSHR P16473 1/20 0.46
ATM Q13315 1/20 0.46
LMNA P02545 1/20 0.44
GSK3B P49841 1/20 0.44
AKR1C3 P42330 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10414698 1.00 MAOA (0.66) MAOAMAOBL3MBTL1TDP1MAPT
SCHEMBL31634592 1.00 MAOA (0.66) MAOAMAOBL3MBTL1TDP1MAPT
SCHEMBL30970619 0.94 MAOA (0.56) MAOAMAOBL3MBTL1TDP1MAPT
SCHEMBL1501398 0.94 MAOA (0.56) MAOAMAOBL3MBTL1TDP1MAPT
SCHEMBL84254 0.94 MAOA (0.56) MAOAMAOBL3MBTL1TDP1MAPT
SCHEMBL42261 0.92 MAOA (0.53) MAOAMAOBL3MBTL1TDP1MAPT
SCHEMBL30950420 0.92 MAOA (0.53) MAOAMAOBL3MBTL1TDP1MAPT
SCHEMBL1655544 0.91 MAOA (0.56) MAOAMAOBL3MBTL1TDP1MAPT
SCHEMBL2435900 0.90 MAOA (0.53) MAOAMAOBL3MBTL1TDP1MAPT
SCHEMBL3625447 0.89 MAOA (0.51) MAOAMAOBL3MBTL1TDP1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 97 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118146113-A Sizing agent and preparation method and application thereof 东华大学 2024-06-07 CN claimed
CN-112661699-B Preparation method of intermediate of roxasistat 扬子江药业集团有限公司 2022-03-22 CN claimed
CN-108795044-B C-grade VPI impregnating resin for electric locomotive and preparation method thereof 丹阳市沃德立电工材料有限公司 2021-07-20 CN claimed
CN-112661699-A Preparation method of intermediate of roxasistat 扬子江药业集团有限公司 2021-04-16 CN claimed
EP-0315025-A1 Amide-imide copolymers and process for the preparation thereof GENERAL ELECTRIC COMPANY (US) 1989-05-10 EP claimed
US-4281100-A Injection moldable polyetherimide oligomers and method for making GENERAL ELECTRIC COMPANY (US) 1981-07-28 US claimed
JP-1128977-A None JP disclosed
CN-120943583-A Recycled concrete with self-repairing function and preparation method thereof 中交路桥建设有限公司 2025-11-14 CN disclosed
CN-119253073-A High-voltage electrolyte and lithium ion battery 合肥国轩高科动力能源有限公司 2025-01-03 CN disclosed
CN-118146113-A Sizing agent and preparation method and application thereof 东华大学 2024-06-07 CN disclosed
US-20240018109-A1 METHOD FOR SYNTHESIS OF ROXADUSTAT AND INTERMEDIATE THEREOF, AND INTERMEDIATE THEREOF JUMPCAN (SHANGHAI) MEDICAL TECHNOLOGY CO., LTD (CN) 2024-01-18 US disclosed
CN-117285464-A Roflumilast intermediate compound and preparation method and application thereof 山东新时代药业有限公司 2023-12-26 CN disclosed
CN-110526813-B Process for producing isoquinoline compounds and intermediates thereof 杭州科巢生物科技有限公司 2022-06-28 CN disclosed
WO-1986002368-A1 AROMATIC POLY(ETHER KETONES) HAVING IMIDE, AMIDE, ESTER, AZO, QUINOXALINE, BENZIMIDAZOLE, BENZOXAZOLE OR BENZOTHIAZOLE GROUPS AND METHOD OF PREPARATION RAYCHEM CORPORATION (US) 1986-04-24 WO disclosed
EP-0178185-A2 Novel aromatic polymers RAYCHEM CORPORATION (a Delaware corporation) (US) 1986-04-16 EP disclosed
EP-0145078-A2 Diphenyl ether herbicides SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) 1985-06-19 EP disclosed
US-4281100-A Injection moldable polyetherimide oligomers and method for making GENERAL ELECTRIC COMPANY (US) 1981-07-28 US disclosed
US-4233435-A SOLVENT-FREE PROCESS WHICH INCLUDES A MONOHYDRIC ALCOHOL FOR PREPARING PHTHALATE-MOIETY BASED RESIN FOR COATING ELECTRICAL CONDUCTORS GENERAL ELECTRIC COMPANY (US) 1980-11-11 US disclosed
US-4217281-A Imide carbonyl compounds and method for making GENERAL ELECTRIC COMPANY (US) 1980-08-12 US disclosed
US-4128574-A FROM AN IMIDE GENERAL ELECTRIC COMPANY (US) 1978-12-05 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240018109-A1 METHOD FOR SYNTHESIS OF ROXADUSTAT AND INTERMEDIATE THEREOF, AND INTERMEDIATE THEREOF SRM, SMS, SMOX MAOA 28/4885MAOB 79/4885L3MBTL1 1195/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.