SCHEMBL16556664

SCHEMBL16556664

CCCCC1(CCCC)c2ccccc2-c2ccc(/C(C)=N/OC(C)=O)cc21

nearest known ligand 0.42

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
▸ PDK2 Q15119 19/20 0.42
▸ APEX1 P27695 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18012817 0.94 PDK2 (0.36) PDK2
SCHEMBL17084360 0.93 PDK2 (0.41) PDK2APEX1
SCHEMBL17056224 0.93 PDK2 (0.41) PDK2APEX1
SCHEMBL26818789 0.89 PDK2 (0.39) PDK2APEX1
SCHEMBL18235853 0.89 PDK2 (0.39) PDK2APEX1
SCHEMBL17056229 0.86 PDK2 (0.40) PDK2APEX1
SCHEMBL17056201 0.86 PDK2 (0.41) PDK2
SCHEMBL13538673 0.86 PDK2 (0.38) PDK2APEX1
SCHEMBL17084340 0.85 PDK2 (0.43) PDK2
SCHEMBL17086822 0.84 PDK2 (0.46) PDK2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9316906-B2 Fluorene oxime ester compound, photopolymerization initiator and photoresist composition containing the same KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) 2016-04-19 — — US disclosed
US-9316906-B2 Fluorene oxime ester compound, photopolymerization initiator and photoresist composition containing the same KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) 2016-04-19 — — US disclosed
US-20150111152-A1 NOVEL FLUORENE OXIME ESTER COMPOUND, PHOTOPOLYMERIZATION INITIATOR AND PHOTORESIST COMPOSITION CONTAINING THE SAME KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) 2015-04-23 — — US disclosed
US-20150111152-A1 NOVEL FLUORENE OXIME ESTER COMPOUND, PHOTOPOLYMERIZATION INITIATOR AND PHOTORESIST COMPOSITION CONTAINING THE SAME KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) 2015-04-23 — — US disclosed
EP-2845845-A1 NOVEL OXIMESTER FLUORINE COMPOUND, AND PHOTOPOLYMERIZATION INITIATOR AND PHOTORESIST COMPOSITION COMPRISING SAME Korea Research Institute of Chemical Technology (KR) 2015-03-11 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150111152-A1 NOVEL FLUORENE OXIME ESTER COMPOUND, PHOTOPOLYMERIZATION INITIATOR AND PHOTORESIST COMPOSITION CONTAINING THE SAME PPOX, FTO, PAM PDK2 419/4885APEX1 2298/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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