Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 2/20 | 0.45 |
| ▸ | CA1 | P00915 | 1/20 | 0.45 |
| ▸ | CPB2 | Q96IY4 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | MGAM | O43451 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | SI | P14410 | 1/20 | 0.37 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.37 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.35 |
| ▸ | PPARG | P37231 | 2/20 | 0.35 |
| ▸ | CAD | P27708 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20704277 | 1.00 | CA2 (0.45) | CA2CA1CPB2ALDH1A1MEN1 | |
| SCHEMBL21052387 | 0.88 | CA2 (0.50) | CA2CA1CPB2ALDH1A1MEN1 | |
| SCHEMBL1405922 | 0.86 | CPB2 (0.42) | CPB2ALDH1A1MEN1NPC1KMT2A | |
| SCHEMBL17523695 | 0.84 | HDAC1 (0.44) | CA2CA1CPB2ALDH1A1MEN1 | |
| Acetic Acid SCHEMBL3158726 | 0.84 | ALDH1A1 (0.42) | CPB2ALDH1A1MEN1NPC1KMT2A | |
| Acetic Acid SCHEMBL1820606 | 0.84 | ALDH1A1 (0.42) | CPB2ALDH1A1MEN1NPC1KMT2A | |
| SCHEMBL28078262 | 0.84 | HDAC1 (0.44) | CA2CA1CPB2ALDH1A1MEN1 | |
| SCHEMBL17617131 | 0.84 | CA2 (0.52) | CA2CA1CPB2ALDH1A1MEN1 | |
| SCHEMBL9372700 | 0.84 | CA2 (0.47) | CA2CA1ALDH1A1GAASOAT1 | |
| SCHEMBL13575662 | 0.84 | CA2 (0.52) | CA2CA1CPB2ALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101433308-A | O/W type food level beta-carotene microemulsion carrier and preparation method thereof | UNIV SHANGHAI JIAOTONG (CN) | 2009-05-20 | — | — | CN | claimed |
| EP-0423873-A2 | Process for making improved citrus aqueous essence | THE PROCTER & GAMBLE COMPANY (US) | 1991-04-24 | — | — | EP | claimed |
| US-4970085-A | FLAVORS | THE PROCTER & GAMBLE COMPANY (US) | 1990-11-13 | — | — | US | claimed |
| WO-2011073929-A1 | 6-(2-FURYL)-3-METHYL-4-OXO-1,5,6,7-TETRAHYDROINDOLE-2-CARBOXYLATE DERIVATIVES AND USES THEREOF | ISTITUTO EUROPEO DI ONCOLOGIA S.R.L. (IT) | 2011-06-23 | — | — | WO | disclosed |
| WO-2011045265-A2 | SPIROCYCLIC DERIVATIVES AS HISTONE DEACETYLASE INHIBITORS | DAC S.R.L. (IT) | 2011-04-21 | — | — | WO | disclosed |
| CN-101433308-A | O/W type food level beta-carotene microemulsion carrier and preparation method thereof | UNIV SHANGHAI JIAOTONG (CN) | 2009-05-20 | — | — | CN | disclosed |
| CN-101433308-A | O/W type food level beta-carotene microemulsion carrier and preparation method thereof | UNIV SHANGHAI JIAOTONG (CN) | 2009-05-20 | — | — | CN | disclosed |
| US-6949546-B2 | N-ureidoheterocycloalkyl-piperidines as modulators of chemokine receptor activity | BRISTOL-MYERS SQUIBB PHARMA COMPANY (US) | 2005-09-27 | — | — | US | disclosed |
| US-20040058961-A1 | N-ureidoheterocycloalkyl-piperidines as modulators of chemokine receptor activity | KO SOO S (US) | 2004-03-25 | — | — | US | disclosed |
| US-6627629-B2 | Useful for the treatment or prevention of asthma and other allergic diseases. | BRISTOL-MYERS SQUIBB PHARMA | 2003-09-30 | — | — | US | disclosed |
| EP-1296978-A2 | N-UREIDOHETEROCYCLOAKLYL-PIPERIDINES AS MODULATORS OF CHEMOKINE RECEPTOR ACTIVITY | BRISTOL-MYERS SQUIBB COMPANY (US) | 2003-04-02 | — | — | EP | disclosed |
| US-20030032654-A1 | N-ureidoheterocycloalkyl-piperidines as modulators of chemokine receptor activity | BRISTOL-MYERS SQUIBB PHARMA COMPANY | 2003-02-13 | — | — | US | disclosed |
| WO-2002002525-A2 | N-UREIDOHETEROCYCLOAKLYL-PIPERIDINES AS MODULATORS OF CHEMOKINE RECEPTOR ACTIVITY | BRISTOL-MYERS SQUIBB PHARMA COMPANY (US) | 2002-01-10 | — | — | WO | disclosed |
| EP-0423873-A2 | Process for making improved citrus aqueous essence | THE PROCTER & GAMBLE COMPANY (US) | 1991-04-24 | — | — | EP | disclosed |
| US-4970085-A | FLAVORS | THE PROCTER & GAMBLE COMPANY (US) | 1990-11-13 | — | — | US | disclosed |
| US-4929754-A | CARDIOVASCULAR DISORDERS, ANTICOAGULANTS, ANTITUMOR AGENTS | DR. KARL THOMAE GMBH (DE) | 1990-05-29 | — | — | US | disclosed |
| US-4820705-A | ANTITUMOR, CARDIOVASCULR DISORDERS | DR. KARL THOMAE GMBH (DE) | 1989-04-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040058961-A1 | N-ureidoheterocycloalkyl-piperidines as modulators of chemokine receptor activity | CCR3, CCR1, ACKR3 | CA2 1487/4885CA1 3245/4885CPB2 1612/4885 |
| US-20030032654-A1 | N-ureidoheterocycloalkyl-piperidines as modulators of chemokine receptor activity | CCR3, CCR1, ACKR3 | CA2 1487/4885CA1 3245/4885CPB2 1612/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.