SCHEMBL16558140

SCHEMBL16558140

N#Cc1ccc2c3ccc(-c4cc5c6ccccc6c(-c6cccnc6)cc5c5ccccc45)cc3n(-c3ccccc3)c2c1

nearest known ligand 0.45

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
CYP11B2 P19099 9/20 0.45
CYP11B1 P15538 7/20 0.45
CYP19A1 P11511 2/20 0.45
MAPK1 P28482 1/20 0.45
CYP17A1 P05093 1/20 0.44
FLT3 P36888 2/20 0.42
CHRNB2 P17787 1/20 0.40
CHRNA5 P30532 1/20 0.40
CHRNA4 P43681 1/20 0.40
ABCG2 Q9UNQ0 2/20 0.39
NEK1 Q96PY6 1/20 0.39
KDM4E B2RXH2 1/20 0.38
GLA P06280 1/20 0.38
GAA P10253 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16558149 0.96 CYP11B2 (0.46) CYP11B2CYP11B1CYP19A1MAPK1CYP17A1
SCHEMBL16561064 0.89 CYP11B2 (0.45) CYP11B2CYP11B1CYP19A1MAPK1CYP17A1
SCHEMBL16558139 0.89 TDP2 (0.39) CYP19A1FLT3KDM4E
SCHEMBL16455810 0.87 CYP11B2 (0.46) CYP11B2CYP11B1CYP19A1MAPK1CYP17A1
SCHEMBL16558161 0.85 TDP2 (0.37) CYP19A1KDM4E
SCHEMBL16561025 0.85 CYP11B2 (0.46) CYP11B2CYP11B1CYP19A1MAPK1CYP17A1
SCHEMBL16558150 0.85 TDP2 (0.38) CYP19A1KDM4E
SCHEMBL16558168 0.84 TDP2 (0.36) CYP11B2CYP11B1CYP19A1FLT3KDM4E
SCHEMBL16558162 0.84 METAP2 (0.37) CYP11B2CYP11B1CYP19A1FLT3
SCHEMBL16558153 0.84 TDP2 (0.39) MAPK1FLT3ABCG2KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9825231-B2 Condensed cyclic compound and organic light-emitting device including the same SAMSUNG DISPLAY CO., LTD. (KR) 2017-11-21 US disclosed
US-9825231-B2 Condensed cyclic compound and organic light-emitting device including the same SAMSUNG DISPLAY CO., LTD. (KR) 2017-11-21 US disclosed
US-20150069347-A1 CONDENSED CYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME SAMSUNG DISPLAY CO., LTD. (KR) 2015-03-12 US disclosed
US-20150069347-A1 CONDENSED CYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME SAMSUNG DISPLAY CO., LTD. (KR) 2015-03-12 US disclosed