Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAAA | Q02083 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.38 |
| ▸ | MGAM | O43451 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | SI | P14410 | 1/20 | 0.38 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.38 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | BLM | P54132 | 1/20 | 0.35 |
| ▸ | WRN | Q14191 | 1/20 | 0.35 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.33 |
| ▸ | FFAR3 | O14843 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27605067 | 0.91 | TSHR (0.46) | NAAAALDH1A1MGAMGAASI | |
| Potassium Ion SCHEMBL29140513 | 0.87 | MEN1 (0.33) | NAAAMGAMGAASIMGAM2 | |
| SCHEMBL166990 | 0.82 | ALDH1A1 (0.64) | NAAAALDH1A1MGAMGAASI | |
| SCHEMBL288874 | 0.81 | NAAA (0.38) | NAAAALDH1A1MGAMGAASI | |
| SCHEMBL27814845 | 0.79 | MAPT (0.48) | NAAAALDH1A1TDP1LMNAMAPT | |
| SCHEMBL4603931 | 0.79 | PDE4A (0.50) | NAAATDP1LMNA | |
| SCHEMBL386957 | 0.78 | NAAA (0.39) | NAAAALDH1A1MGAMGAASI | |
| SCHEMBL11715098 | 0.77 | OR51E2 (0.40) | NAAAALDH1A1MGAMGAASI | |
| SCHEMBL28298194 | 0.77 | MGAM (0.50) | ALDH1A1MGAMGAASIMGAM2 | |
| SCHEMBL28778976 | 0.76 | NAAA (0.38) | NAAAALDH1A1MGAMGAASI |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-100497315-C | Preparation of (R)-(-)-apomorphine | UNIV EAST CHINA SCIENCE & TECH (CN) | 2009-06-10 | — | — | CN | claimed |
| CN-1680330-A | Preparation of (R)-(-)-apomorphine | HUADONG SCIENCE & ENGINEERING (CN) | 2005-10-12 | — | — | CN | claimed |
| US-8912179-B2 | Heterocyclyl compounds as histamine H3 receptor ligands | SUVEN LIFE SCIENCES LIMITED (IN) | 2014-12-16 | — | — | US | disclosed |
| US-20140148440-A1 | HETEROCYCLYL COMPOUNDS AS HISTAMINE H3 RECEPTOR LIGANDS | SUVEN LIFE SCIENCES LIMITED (IN) | 2014-05-29 | — | — | US | disclosed |
| EP-2611444-A1 | HETEROCYCLYL COMPOUNDS AS HISTAMINE H3 RECEPTOR LIGANDS | Suven Life Sciences Limited (IN) | 2013-07-10 | — | — | EP | disclosed |
| WO-2012029070-A1 | HETEROCYCLYL COMPOUNDS AS HISTAMINE H3 RECEPTOR LIGANDS | SUVEN LIFE SCIENCES LIMITED (IN) | 2012-03-08 | — | — | WO | disclosed |
| CN-100497315-C | Preparation of (R)-(-)-apomorphine | UNIV EAST CHINA SCIENCE & TECH (CN) | 2009-06-10 | — | — | CN | disclosed |
| CN-100439337-C | Phenyl substituted piperidine compounds for use as PPAR activators | PFIZER PROD INC (US) | 2008-12-03 | — | — | CN | disclosed |
| CN-1717389-A | Phenyl substituted piperidine compounds for use as PPAR activators | PFIZER PROD INC (US) | 2006-01-04 | — | — | CN | disclosed |
| CN-1680330-A | Preparation of (R)-(-)-apomorphine | HUADONG SCIENCE & ENGINEERING (CN) | 2005-10-12 | — | — | CN | disclosed |
| WO-1995005154-A1 | CLEANSING COMPOSITION | UNILEVER PLC (GB) | 1995-02-23 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140148440-A1 | HETEROCYCLYL COMPOUNDS AS HISTAMINE H3 RECEPTOR LIGANDS | HRH3, HRH4, HRH1 | NAAA 659/4885ALDH1A1 1573/4885MGAM 4554/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.