Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAAA | Q02083 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | MGAM | O43451 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | SI | P14410 | 1/20 | 0.36 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.36 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.34 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | BLM | P54132 | 1/20 | 0.34 |
| ▸ | WRN | Q14191 | 1/20 | 0.34 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.32 |
| ▸ | FFAR3 | O14843 | 1/20 | 0.32 |
| ▸ | ESR1 | P03372 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28788296 | 0.80 | NAAA (0.35) | NAAAALDH1A1ALOX15MGAMGAA | |
| SCHEMBL1535416 | 0.78 | SLC7A5 (0.42) | NAAAALDH1A1ALOX15MGAMGAA | |
| SCHEMBL5688404 | 0.77 | PTGS1 (0.44) | NAAAALDH1A1ALOX15MGAMGAA | |
| SCHEMBL28679561 | 0.77 | NAAA (0.33) | NAAAALDH1A1ALOX15MGAMGAA | |
| SCHEMBL386957 | 0.76 | NAAA (0.39) | NAAAALDH1A1ALOX15MGAMGAA | |
| SCHEMBL165589 | 0.76 | NAAA (0.39) | NAAAALDH1A1ALOX15MGAMGAA | |
| SCHEMBL6136549 | 0.75 | DPP4 (0.42) | — | |
| SCHEMBL3498360 | 0.75 | NAAA (0.32) | NAAAALDH1A1ALOX15MGAMGAA | |
| SCHEMBL4004371 | 0.75 | NAAA (0.32) | NAAAALDH1A1ALOX15MGAMGAA | |
| SCHEMBL6136333 | 0.75 | SLC7A5 (0.50) | NAAAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101784266-B | Bupropion hydrobromide and therapeutic applications | BIOVAIL LAB INT SRL | 2012-07-18 | — | — | CN | disclosed |
| CN-101903016-A | Bupropion hydrobromide and therapeutic uses | BIOVAIL LAB INT SRL | 2010-12-01 | — | — | CN | disclosed |
| CN-101784266-A | The application of bupropion hydrobromide and treatment | BIOVAIL LAB INT SRL | 2010-07-21 | — | — | CN | disclosed |
| CN-101534808-A | Modified release formulations of bupropion salts | BIOVAIL LAB INT SRL (BB) | 2009-09-16 | — | — | CN | disclosed |