Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DAGLA | Q9Y4D2 | 1/20 | 0.38 |
| ▸ | SPHK1 | Q9NYA1 | 4/20 | 0.34 |
| ▸ | SPHK2 | Q9NRA0 | 3/20 | 0.34 |
| ▸ | POLB | P06746 | 2/20 | 0.33 |
| ▸ | FASN | P49327 | 1/20 | 0.33 |
| ▸ | GMNN | O75496 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | THPO | P40225 | 1/20 | 0.32 |
| ▸ | MTOR | P42345 | 1/20 | 0.32 |
| ▸ | BLM | P54132 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12302384 | 1.00 | DAGLA (0.38) | DAGLASPHK1SPHK2POLBFASN | |
| SCHEMBL12302325 | 0.92 | DAGLA (0.34) | DAGLA | |
| SCHEMBL12302319 | 0.92 | DAGLA (0.34) | DAGLA | |
| SCHEMBL15381137 | 0.90 | SPHK1 (0.39) | DAGLASPHK1SPHK2POLBGMNN | |
| SCHEMBL12302327 | 0.83 | DAGLA (0.34) | DAGLASPHK1POLBGMNNLMNA | |
| SCHEMBL12580607 | 0.81 | CTSK (0.32) | DAGLA | |
| SCHEMBL15381102 | 0.81 | CTSK (0.32) | DAGLA | |
| SCHEMBL17682895 | 0.79 | LMNA (0.35) | DAGLASPHK1SPHK2POLBFASN | |
| SCHEMBL13644871 | 0.79 | — | — | |
| SCHEMBL20019591 | 0.78 | SPHK1 (0.40) | DAGLASPHK1SPHK2POLBFASN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180170957-A1 | HUMAN iNKT CELL ACTIVATION USING GLYCOLIPIDS | ACADEMIA SINICA (TW) | 2018-06-21 | — | — | US | disclosed |
| US-9879042-B2 | Human iNKT cell activation using glycolipids | ACADEMIA SINICA (TW) | 2018-01-30 | — | — | US | disclosed |
| US-20170360924-A1 | HUMAN iNKT CELL ACTIVATION USING GLYCOLIPIDS WITH ALTERED GLYCOSYL GROUPS | ACADEMIA SINICA (TW) | 2017-12-21 | — | — | US | disclosed |
| US-9782476-B2 | Human iNKT cell activation using glycolipids with altered glycosyl groups | ACADEMIA SINICA (TW) | 2017-10-10 | — | — | US | disclosed |
| US-20160102116-A1 | HUMAN iNKT CELL ACTIVATION USING GLYCOLIPIDS | ACADEMIA SINICA (TW) | 2016-04-14 | — | — | US | disclosed |
| US-20150071960-A1 | HUMAN iNKT CELL ACTIVATION USING GLYCOLIPIDS WITH ALTERED GLYCOSYL GROUPS | ACADEMIA SINICA (TW) | 2015-03-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170360924-A1 | HUMAN iNKT CELL ACTIVATION USING GLYCOLIPIDS WITH ALTERED GLYCOSYL GROUPS | UGCG, GALK1, B3GAT3 | DAGLA 71/4885SPHK1 165/4885SPHK2 235/4885 |
| US-20160102116-A1 | HUMAN iNKT CELL ACTIVATION USING GLYCOLIPIDS | CD69, PBK, CCL11 | DAGLA 25/4885SPHK1 33/4885SPHK2 43/4885 |
| US-20150071960-A1 | HUMAN iNKT CELL ACTIVATION USING GLYCOLIPIDS WITH ALTERED GLYCOSYL GROUPS | UGCG, GALK1, B3GAT3 | DAGLA 71/4885SPHK1 165/4885SPHK2 235/4885 |
| US-20180170957-A1 | HUMAN iNKT CELL ACTIVATION USING GLYCOLIPIDS | CD69, PBK, CCL11 | DAGLA 25/4885SPHK1 33/4885SPHK2 43/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.