⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| 4-(Hydroxyamino)Butanoic Acid SCHEMBL1655977 | 0.81 | — | — | |
| SCHEMBL4941181 | 0.79 | — | — | |
| 4-(Hydroxyamino)Butanoic Acid SCHEMBL28266183 | 0.79 | — | — | |
| SCHEMBL7100034 | 0.77 | TSHR (0.63) | — | |
| SCHEMBL6900773 | 0.77 | TSHR (0.63) | — | |
| SCHEMBL6902609 | 0.77 | TSHR (0.63) | — | |
| SCHEMBL39829 | 0.77 | TSHR (0.63) | — | |
| SCHEMBL6899587 | 0.77 | TSHR (0.63) | — | |
| SCHEMBL20518454 | 0.77 | TSHR (0.63) | — | |
| SCHEMBL109879 | 0.76 | LMNA (0.53) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 67 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040110729-A1 | Primary N-hydroxylamines | NIH | 2004-06-10 | — | — | US | claimed |
| US-6455589-B1 | AN ORALLY ADMINISTRABLE EFFECTIVE UNIT SOLID DOSAGE OF A PRIMARY N-HYDROXYLAMINE OR A SALT, FREE OF NITRONE; USEFUL FOR REDUCING OXIDATIVE DAMAGE OR DELAYING SENESCENCE | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2002-09-24 | — | — | US | claimed |
| US-5646327-A | Method for preparing hydroxylamines using vinylic compounds without base neutralization and reaction mixture produced thereby | EASTMAN KODAK COMPANY (US) | 1997-07-08 | — | — | US | claimed |
| EP-0761647-A2 | Improved method for preparing hydroxylamines using vinylic compounds without base neutralization and reaction mixture produced thereby | EASTMAN KODAK COMPANY (US) | 1997-03-12 | — | — | EP | claimed |
| US-5322948-A | Reacting unsaturated diacid or derivative with hydroxylamine or a salt thereof to form N-hydroxy-2-aminobutane diacid derivative | HOECHST CELANESE CORPORATION (US) | 1994-06-21 | — | — | US | claimed |
| EP-0511446-A2 | Process for preparing pyridinecarboxylic acid derivatives | HOECHST CELANESE CORPORATION (US) | 1992-11-04 | — | — | EP | claimed |
| JP-61068498-A | — | — | None | — | — | JP | disclosed |
| JP-4080298-A | — | — | None | — | — | JP | disclosed |
| US-20230001001-A1 | CONJUGATION OF A CYTOTOXIC DRUG WITH BIS-LINKAGE | HANGZHOU DAC BIOTECH CO., LTD. (CN) | 2023-01-05 | — | — | US | disclosed |
| CN-111482596-B | Copper-containing particle, conductor-forming composition, method for producing conductor, and device | 昭和电工材料株式会社 | 2022-11-22 | — | — | CN | disclosed |
| CN-114728254-A | Polyurea microcapsules and liquid surfactant system containing the same | 西姆莱斯股份公司 | 2022-07-08 | — | — | CN | disclosed |
| CN-114728092-A | Edge block with improved odor performance | 西姆莱斯股份公司 | 2022-07-08 | — | — | CN | disclosed |
| CN-114364773-A | Aromatic oil mixture | 西姆莱斯股份公司 | 2022-04-15 | — | — | CN | disclosed |
| EP-0761647-A2 | Improved method for preparing hydroxylamines using vinylic compounds without base neutralization and reaction mixture produced thereby | EASTMAN KODAK COMPANY (US) | 1997-03-12 | — | — | EP | disclosed |
| WO-1996035737-A1 | PROCESS FOR PREPARING ASPARTIC ACID POLYCONDENSATES | BASF AKTIENGESELLSCHAFT (DE) | 1996-11-14 | — | — | WO | disclosed |
| US-5531934-A | POLYASPARTIC ACID AND POLYGLUTAMIC ACID WITH PYROPHOSPHATE FOR CORROSION RESISTANCE OF FERROUS METALS | ROHM & HAAS COMPANY (US) | 1996-07-02 | — | — | US | disclosed |
| WO-1996014330-A1 | AMINO ACID NUCLEIC ACIDS | ICNPHARMACEUTICALS (US) | 1996-05-17 | — | — | WO | disclosed |
| JP-H0480298-A | DETERGENT COMPOSITION | SHISEIDOU HONE KEEKI KOGYO KK | 1992-03-13 | — | — | JP | disclosed |
| JP-S6168498-A | TRIHYDROXAMIC ACID DERIVATIVE | AKIYAMA MASAYASU | 1986-04-08 | — | — | JP | disclosed |
| JP-H00480298-A | — | — | 0001-01-01 | — | — | JP | disclosed |