Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HINT1 | P49773 | 5/20 | 0.49 |
| ▸ | NT5E | P21589 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 2/20 | 0.49 |
| ▸ | GSK3A | P49840 | 2/20 | 0.47 |
| ▸ | RPS6KA3 | P51812 | 2/20 | 0.47 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.47 |
| ▸ | TGM2 | P21980 | 1/20 | 0.46 |
| ▸ | PNP | P00491 | 1/20 | 0.45 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.45 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.45 |
| ▸ | KRAS | P01116 | 5/20 | 0.44 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.44 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14896399 | 0.88 | HINT1 (0.49) | HINT1NT5EHPGDGSK3ARPS6KA3 | |
| SCHEMBL6037194 | 0.85 | HINT1 (0.56) | HINT1NT5EHPGDGSK3ARPS6KA3 | |
| SCHEMBL13715923 | 0.84 | HPGD (0.54) | HINT1NT5EHPGDGSK3ARPS6KA3 | |
| SCHEMBL3918431 | 0.84 | HPGD (0.54) | HINT1NT5EHPGDGSK3ARPS6KA3 | |
| SCHEMBL13744021 | 0.84 | HPGD (0.54) | HINT1NT5EHPGDGSK3ARPS6KA3 | |
| SCHEMBL16561357 | 0.83 | ADORA3 (0.59) | TAS1R3TAS1R1ADORA2AADORA2B | |
| SCHEMBL6748231 | 0.81 | HINT1 (0.47) | HINT1NT5EHPGDGSK3ARPS6KA3 | |
| SCHEMBL7101380 | 0.81 | HPGD (0.60) | HINT1NT5EHPGDGSK3ARPS6KA3 | |
| SCHEMBL23679991 | 0.80 | HINT1 (0.61) | HINT1NT5EHPGDGSK3ARPS6KA3 | |
| SCHEMBL1639395 | 0.80 | HINT1 (0.61) | HINT1NT5EHPGDGSK3ARPS6KA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8981076-B2 | Synthesis of N-FMOC protected deoxy nucleosides, ribo nucleosides, modified deoxy and ribo nucleosides, and phosphoramidites, and their use in oligonucleotide synthesis | CHEMGENES CORPORATION (US) | 2015-03-17 | — | — | US | disclosed |