SCHEMBL1656177

SCHEMBL1656177

C=Cc1nc2cccc(C=C)c2[nH]1

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ RAB9A P51151 7/20 0.36
▸ KDM4E B2RXH2 5/20 0.36
▸ LMNA P02545 2/20 0.36
▸ ALDH1A1 P00352 5/20 0.32
▸ NPC1 O15118 6/20 0.32
▸ POLB P06746 4/20 0.32
▸ SMN1; SMN2 Q16637 3/20 0.32
▸ CASP3 P42574 2/20 0.32
▸ SENP7 Q9BQF6 2/20 0.32
▸ SENP6 Q9GZR1 2/20 0.32
▸ GAA P10253 2/20 0.32
▸ MAPT P10636 2/20 0.32
▸ BLM P54132 1/20 0.32
▸ SENP8 Q96LD8 1/20 0.32
▸ TDP1 Q9NUW8 1/20 0.32
▸ NPSR1 Q6W5P4 1/20 0.32
▸ HPGD P15428 2/20 0.32
▸ NFKB1 P19838 1/20 0.32
▸ HTT P42858 1/20 0.32
▸ RECQL P46063 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15968319 0.80 NPC1 (0.37) RAB9AKDM4ELMNAALDH1A1NPC1
SCHEMBL10897961 0.80 PARP1 (0.41) RAB9AKDM4EALDH1A1NPC1POLB
SCHEMBL5142300 0.76 — —
SCHEMBL10609521 0.76 NPC1 (0.50) RAB9AKDM4EALDH1A1NPC1SMN1; SMN2
SCHEMBL9636432 0.73 GAA (0.54) RAB9AKDM4ENPC1GAAMAPT
SCHEMBL29195098 0.72 PARP1 (0.36) RAB9AKDM4EALDH1A1NPC1SMN1; SMN2
SCHEMBL1568280 0.71 ALDH1A1 (0.59) RAB9AKDM4ELMNAALDH1A1NPC1
SCHEMBL1656175 0.70 ADAMTS5 (0.34) RAB9AKDM4ELMNAALDH1A1NPC1
SCHEMBL31051335 0.69 RAB9A (0.61) RAB9AKDM4ELMNAALDH1A1NPC1
SCHEMBL18000155 0.67 KDM4E (0.38) KDM4ELMNAALDH1A1POLBSMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4391741-B1 GLASS BARRIER LAYER PRODUCT, AND MANUFACTURE METHOD AUSTRIA TECH & SYSTEM TECH (AT) 2026-02-25 — — EP disclosed
EP-4640016-A1 GLASS BARRIER LAYER PRODUCT, AND MANUFACTURE METHOD AT & S Austria Technologie & Systemtechnik Aktiengesellschaft (AT) 2025-10-29 — — EP disclosed
WO-2025040326-A1 COMPONENT CARRIER WITH HYDROPHOBIC PROTECTION FILM, AND MANUFACTURING METHOD AT & S AUSTRIA TECHNOLOGIE & SYSTEMTECHNIK AKTIENGESELLSCHAFT (AT) 2025-02-27 — — WO disclosed
EP-4514077-A1 COMPONENT CARRIER WITH HYDROPHOBIC PROTECTION FILM, AND MANUFACTURING METHOD AT & S Austria Technologie & Systemtechnik Aktiengesellschaft (AT) 2025-02-26 — — EP disclosed
WO-2024133821-A1 GLASS BARRIER LAYER PRODUCT, AND MANUFACTURE METHOD AT&S AUSTRIA TECHNOLOGIE & SYSTEMTECHNIK AKTIENGESELLSCHAFT (AT) 2024-06-27 — — WO disclosed
EP-4391741-A1 GLASS BARRIER LAYER PRODUCT, AND MANUFACTURE METHOD AT & S Austria Technologie & Systemtechnik Aktiengesellschaft (AT) 2024-06-26 — — EP disclosed
CN-117327312-A High-performance high-proton-conductivity phosphoric acid doped grafted crosslinked membrane and preparation method thereof 吉林大学 2024-01-02 — — CN disclosed
US-7927486-B2 Polymer modified porous substrate for solid phase extraction AGILENT TECHNOLOGIES, INC (US) 2011-04-19 — — US disclosed
EP-1899050-A2 POLAR FUNCTIONIZED POLYMER MODIFIED POROUS SUBSTRATE FOR SOLID PHASE EXTRACTION Varian, Inc. (US) 2008-03-19 — — EP disclosed
US-20080035558-A1 Polymer modified porous substrate for solid phase extraction AGILENT TECHNOLOGIES, INC. 2008-02-14 — — US disclosed
US-7311825-B2 Polymer modified porous substrate for solid phase extraction VARIAN, INC. (US) 2007-12-25 — — US disclosed
WO-2006118887-A2 POLAR FUNCTIONIZED POLYMER MODIFIED POROUS SUBSTRATE FOR SOLID PHASE EXTRACTION VARIAN, INC. (US) 2006-11-09 — — WO disclosed
US-20060247361-A1 Polar functionalized polymer modified porous substrate for solid phase extraction VARIAN, INC. 2006-11-02 — — US disclosed
US-20060247362-A1 Polymer modified porous substrate for solid phase extraction VARIAN, INC. 2006-11-02 — — US disclosed
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