SCHEMBL165629

SCHEMBL165629

CC(C)(OC(=O)c1ccc(SSCl)cc1)c1ccccc1

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP2C19 P33261 2/20 0.39
HIF1A Q16665 1/20 0.39
ALDH1A1 P00352 3/20 0.39
ALOX15 P16050 1/20 0.39
TDP1 Q9NUW8 2/20 0.37
TSHR P16473 2/20 0.37
HSD17B10 Q99714 1/20 0.37
MAPT P10636 3/20 0.37
L3MBTL1 Q9Y468 1/20 0.37
MAPK1 P28482 1/20 0.37
CYP1A2 P05177 1/20 0.37
CYP2D6 P10635 1/20 0.37
TNF P01375 1/20 0.36
KLF5 Q13887 1/20 0.36
NOD1 Q9Y239 1/20 0.36
NPSR1 Q6W5P4 1/20 0.35
HPGD P15428 1/20 0.35
LMNA P02545 2/20 0.34
RAB9A P51151 1/20 0.34
F2 P00734 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29324959 0.79 NPC1 (0.49) CYP2C19HIF1AALDH1A1ALOX15TDP1
SCHEMBL25561426 0.76 ALDH1A1 (0.50) CYP2C19HIF1AALDH1A1ALOX15TDP1
SCHEMBL25779634 0.76 CYP2C19 (0.43) CYP2C19HIF1AALDH1A1ALOX15TDP1
SCHEMBL25780248 0.75 CYP2C19 (0.42) CYP2C19HIF1AALDH1A1ALOX15TDP1
SCHEMBL11988598 0.74 CYP2C19 (0.41) CYP2C19HIF1AALDH1A1ALOX15TDP1
SCHEMBL28700661 0.71 ALDH1A1 (0.52) CYP2C19HIF1AALDH1A1ALOX15TDP1
SCHEMBL14062636 0.71 CYP17A1 (0.48) CYP2C19HIF1AALDH1A1TDP1TSHR
SCHEMBL13704323 0.70 ALDH1A1 (0.48) CYP2C19HIF1AALDH1A1ALOX15TSHR
SCHEMBL28787338 0.70 RXRA (0.46) CYP2C19HIF1AALDH1A1ALOX15TDP1
SCHEMBL4734192 0.70 NSD2 (0.54) CYP2C19HIF1AALDH1A1ALOX15TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3088498-A1 USE OF STAR POLYMERS The Lubrizol Corporation (US) 2016-11-02 EP disclosed
EP-2610332-B1 Star polymer and lubricating composition thereof LUBRIZOL CORP (US) 2016-06-29 EP disclosed
EP-1985688-B1 Antiwear polymer and lubricating composition thereof LUBRIZOL CORP (US) 2016-04-20 EP disclosed
US-20150148275-A1 STAR POLYMER AND LUBRICATING COMPOSITION THEREOF LUBRIZOL CORP (US) 2015-05-28 US disclosed
US-8937035-B2 Star polymer and lubricating composition thereof THE LUBRIZOL CORPORATION (US) 2015-01-20 US disclosed
US-20120220506-A1 Star Polymer and Lubricating Composition Thereof THE LUBRIZOL CORPORATION (US) 2012-08-30 US disclosed
WO-2012030616-A1 STAR POLYMER AND LUBRICATING COMPOSITION THEREOF THE LUBRIZOL CORPORATION (US) 2012-03-08 WO disclosed
EP-1985688-A1 Antiwear polymer and lubricating composition thereof The Lubrizol Corporation (US) 2008-10-29 EP disclosed