Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | HSP90AA1 | P07900 | 6/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | BRD4 | O60885 | 1/20 | 0.37 |
| ▸ | CA12 | O43570 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | CA9 | Q16790 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16569373 | 0.95 | HSP90AA1 (0.41) | ALDH1A1CYP2C19HSP90AA1 | |
| SCHEMBL16569200 | 0.92 | KDM4E (0.42) | ALDH1A1TSHRKMT2AHSP90AA1L3MBTL1 | |
| SCHEMBL16569651 | 0.88 | HSP90AA1 (0.44) | KMT2AHSP90AA1 | |
| SCHEMBL24321350 | 0.86 | MEN1 (0.47) | ALDH1A1TSHRKMT2AHSP90AA1L3MBTL1 | |
| SCHEMBL18561685 | 0.85 | HSP90AA1 (0.40) | ALDH1A1TSHRKMT2AHSP90AA1L3MBTL1 | |
| SCHEMBL24321184 | 0.85 | HSP90AA1 (0.46) | ALDH1A1TSHRKMT2AHSP90AA1L3MBTL1 | |
| SCHEMBL17293918 | 0.85 | L3MBTL1 (0.40) | ALDH1A1TSHRKMT2AHSP90AA1L3MBTL1 | |
| SCHEMBL24321134 | 0.84 | HSP90AA1 (0.47) | ALDH1A1TSHRKMT2AHSP90AA1L3MBTL1 | |
| SCHEMBL24321700 | 0.84 | HSP90AA1 (0.44) | ALDH1A1HSP90AA1 | |
| SCHEMBL23135232 | 0.83 | HSP90AA1 (0.41) | HSP90AA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3035938-A1 | TARGETED THERAPEUTICS | Synta Pharmaceuticals Corp. (US) | 2016-06-29 | — | — | EP | disclosed |
| WO-2015038649-A1 | TARGETED THERAPEUTICS | SYNTA PHARMACEUTICALS CORP. (US) | 2015-03-19 | — | — | WO | disclosed |