Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | BRD4 | O60885 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | HSP90AA1 | P07900 | 7/20 | 0.39 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.37 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15525674 | 0.93 | HSP90AA1 (0.42) | BRD4ALDH1A1TSHRSMN1; SMN2HSP90AA1 | |
| SCHEMBL17293963 | 0.91 | HSP90AA1 (0.42) | BRD4SMN1; SMN2KDM4EHSP90AA1HSP90AB1 | |
| SCHEMBL16569200 | 0.89 | KDM4E (0.42) | L3MBTL1ALDH1A1MEN1KMT2AALOX15 | |
| SCHEMBL24321134 | 0.87 | HSP90AA1 (0.47) | L3MBTL1ALDH1A1MEN1KMT2AALOX15 | |
| SCHEMBL24321350 | 0.87 | MEN1 (0.47) | L3MBTL1ALDH1A1MEN1KMT2ATSHR | |
| SCHEMBL18561685 | 0.87 | HSP90AA1 (0.40) | L3MBTL1BRD4ALDH1A1MEN1KMT2A | |
| SCHEMBL24321184 | 0.86 | HSP90AA1 (0.46) | L3MBTL1ALDH1A1MEN1KMT2ATSHR | |
| SCHEMBL15525661 | 0.86 | HSP90AA1 (0.41) | BRD4ALDH1A1KDM4EHSP90AA1HSP90AB1 | |
| SCHEMBL24321700 | 0.85 | HSP90AA1 (0.44) | ALDH1A1KDM4ETDP1HSP90AA1HSP90AB1 | |
| SCHEMBL16569876 | 0.85 | ALDH1A1 (0.44) | L3MBTL1BRD4ALDH1A1KMT2ATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015184246-A1 | TARGETED THERAPEUTICS | SYNTA PHARMACEUTICALS CORP. (US) | 2015-12-03 | — | — | WO | disclosed |