Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.34 |
| ▸ | TSHR | P16473 | 3/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 2/20 | 0.30 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL277661 | 0.96 | ALDH1A1 (0.33) | ALDH1A1TSHRTHRB | |
| SCHEMBL4357945 | 0.89 | ALDH1A1 (0.36) | ALDH1A1TSHRTP53HIF1AHSD17B10 | |
| SCHEMBL259146 | 0.87 | ALDH1A1 (0.32) | ALDH1A1TSHRTP53HIF1AHSD17B10 | |
| SCHEMBL749982 | 0.85 | CA1 (0.33) | ALDH1A1TP53HSD17B10 | |
| SCHEMBL9237706 | 0.83 | CA2 (0.40) | ALDH1A1TSHRTP53HIF1AHSD17B10 | |
| SCHEMBL2757812 | 0.82 | ALDH1A1 (0.33) | ALDH1A1TP53HSD17B10 | |
| SCHEMBL8557919 | 0.80 | — | — | |
| SCHEMBL12703069 | 0.79 | MEN1 (0.46) | ALDH1A1TSHRTHRBTP53HIF1A | |
| Ethylene Glycol SCHEMBL27885940 | 0.78 | TSHR (0.33) | ALDH1A1TSHRTP53HIF1AHSD17B10 | |
| SCHEMBL17453659 | 0.77 | TSHR (0.43) | ALDH1A1TSHRTHRBTP53HIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8980278-B2 | Bio-functionalized stimulus-responsive dissolvable PEG-hydrogels | UNIVERSITAETSKLINIKUM FREIBURG (DE) | 2015-03-17 | — | — | US | disclosed |