Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.30 |
| ▸ | TP53 | P04637 | 2/20 | 0.30 |
| ▸ | TSHR | P16473 | 2/20 | 0.30 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4357945 | 0.89 | ALDH1A1 (0.36) | CA2ALDH1A1TP53TSHRHIF1A | |
| SCHEMBL14277759 | 0.87 | — | — | |
| SCHEMBL259146 | 0.87 | ALDH1A1 (0.32) | CA2ALDH1A1TP53TSHRHIF1A | |
| SCHEMBL16572452 | 0.83 | ALDH1A1 (0.34) | ALDH1A1TP53TSHRHIF1AHSD17B10 | |
| SCHEMBL749982 | 0.81 | CA1 (0.33) | CA2ALDH1A1TP53HSD17B10 | |
| SCHEMBL8557919 | 0.80 | — | — | |
| SCHEMBL12703069 | 0.79 | MEN1 (0.46) | ALDH1A1TP53TSHRHIF1AHSD17B10 | |
| Ethylene Glycol SCHEMBL9237710 | 0.79 | TSHR (0.30) | TSHR | |
| Ethylene Glycol SCHEMBL27885940 | 0.78 | TSHR (0.33) | ALDH1A1TP53TSHRHIF1AHSD17B10 | |
| SCHEMBL16018110 | 0.78 | ALDH1A1 (0.32) | ALDH1A1TP53HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160015838-A1 | Vinylsulfone-based 18F-labeling Compositions and Methods and Uses Thereof | UNIVERSITY OF SOUTHERN CALIFORNIA USC STEVENS (US) | 2016-01-21 | — | — | US | disclosed |
| US-5414135-A | Vinyl sulfone coupling of polyoxyalkylenes to proteins | STERLING WINTHROP INC. (US) | 1995-05-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160015838-A1 | Vinylsulfone-based 18F-labeling Compositions and Methods and Uses Thereof | TST, VARS1, STS | CA2 4778/4885ALDH1A1 1141/4885TP53 981/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.