Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | KDM1A | O60341 | 1/20 | 0.47 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.46 |
| ▸ | F13A1 | P00488 | 1/20 | 0.45 |
| ▸ | TGM2 | P21980 | 1/20 | 0.45 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.45 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.44 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.44 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.44 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.44 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.44 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.44 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.44 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.44 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.44 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.44 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 3/20 | 0.43 |
| ▸ | RAB9A | P51151 | 3/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16573285 | 0.92 | ALDH1A1 (0.48) | POLBAOC3NR1H4HDAC3HDAC4 | |
| SCHEMBL16573272 | 0.84 | EPHX2 (0.55) | POLBSMN1; SMN2ALDH1A1MAPTHPGD | |
| SCHEMBL7688792 | 0.81 | ALDH1A1 (0.47) | POLBAOC3HDAC3HDAC4HDAC1 | |
| SCHEMBL10360661 | 0.80 | SPHK1 (0.49) | POLBKDM1AF13A1TGM2NR1H4 | |
| SCHEMBL28693818 | 0.80 | KDM1A (0.44) | POLBKDM1AF13A1TGM2NR1H4 | |
| Hydrochloric Acid SCHEMBL10360586 | 0.79 | SPHK1 (0.50) | POLBKDM1AAOC3F13A1TGM2 | |
| SCHEMBL30779193 | 0.78 | AOC3 (0.60) | POLBAOC3NR1H4HDAC3HDAC4 | |
| SCHEMBL16573306 | 0.77 | HDAC1 (0.51) | POLBHDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL547069 | 0.76 | CA12 (0.50) | KDM1ANR1H4HDAC3HDAC4HDAC1 | |
| SCHEMBL3658863 | 0.76 | CYP17A1 (0.53) | KDM1ANR1H4HDAC3HDAC1HDAC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2444085-B1 | Diarylhydantoin compounds as androgen receptor antagonists for treatment of cancer | UNIV CALIFORNIA (US) | 2015-03-18 | — | — | EP | disclosed |