Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 2/20 | 0.55 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6535275 | 0.88 | EPHX2 (0.57) | EPHX2POLBKMT2ASMN1; SMN2ALDH1A1 | |
| SCHEMBL16573271 | 0.84 | POLB (0.49) | POLBSMN1; SMN2ALDH1A1HPGDMAPT | |
| SCHEMBL22921868 | 0.83 | TSHR (0.58) | EPHX2KMT2AALDH1A1HTTMAPT | |
| SCHEMBL9054540 | 0.81 | EPHX2 (0.53) | EPHX2 | |
| SCHEMBL4512426 | 0.80 | EPHX2 (0.52) | EPHX2SMN1; SMN2ALDH1A1HTTHPGD | |
| Hydrochloric Acid SCHEMBL10361237 | 0.79 | EPHX2 (0.53) | EPHX2ALDH1A1HTTHPGD | |
| SCHEMBL17064261 | 0.78 | EPHX2 (0.55) | EPHX2SMN1; SMN2ALDH1A1HTTHPGD | |
| SCHEMBL12510584 | 0.78 | SMN1; SMN2 (0.53) | EPHX2SMN1; SMN2HTTHPGD | |
| SCHEMBL8896434 | 0.78 | HSD17B10 (0.67) | EPHX2KMT2AHPGD | |
| SCHEMBL393227 | 0.78 | EPHX2 (0.56) | EPHX2KMT2ASMN1; SMN2ALDH1A1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2444085-B1 | Diarylhydantoin compounds as androgen receptor antagonists for treatment of cancer | UNIV CALIFORNIA (US) | 2015-03-18 | — | — | EP | disclosed |