Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.67 |
| ▸ | CYP4A11 | Q02928 | 3/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | CYP4F2 | P78329 | 2/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8658445 | 0.93 | HSD17B10 (0.58) | HSD17B10CYP4A11KMT2ACYP4F2GAA | |
| SCHEMBL168858 | 0.89 | KMT2A (0.59) | HSD17B10CYP4A11KMT2ACYP4F2EPHX2 | |
| SCHEMBL22921868 | 0.89 | TSHR (0.58) | HSD17B10CYP4A11KMT2ACYP4F2EPHX2 | |
| SCHEMBL803447 | 0.83 | HSD17B10 (0.63) | HSD17B10CYP4A11KMT2ACYP4F2MAPK1 | |
| SCHEMBL12508639 | 0.82 | TSHR (0.50) | CYP4A11CYP4F2EPHX2TSHRL3MBTL1 | |
| SCHEMBL1928824 | 0.82 | PLAAT3 (0.51) | CYP4A11CYP4F2TDP1EPHX2TSHR | |
| SCHEMBL3456495 | 0.82 | CYP4A11 (0.53) | HSD17B10CYP4A11KMT2ACYP4F2EPHX2 | |
| SCHEMBL1863579 | 0.82 | CALM1 (0.55) | HSD17B10CYP4A11CYP4F2EPHX2TSHR | |
| SCHEMBL1866015 | 0.82 | CYP4A11 (0.50) | HSD17B10CYP4A11KMT2ACYP4F2TDP1 | |
| SCHEMBL3409184 | 0.82 | CYP4A11 (0.68) | HSD17B10CYP4A11KMT2ACYP4F2EPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5597848-A | PLATELET AGGREGATION INHIBITORS, ANTITHROMBOTIC AGENTS, ANTIASTHMATIC AGENTS, ANTIALLERGIC AGENTS | HOKURIKU SEIYAKU CO., LTD. (JP) | 1997-01-28 | — | — | US | disclosed |
| EP-0663392-A1 | BENZENESULFONAMIDE DERIVATIVE AND USE THEREOF | HOKURIKU SEIYAKU CO., LTD. (JP) | 1995-07-19 | — | — | EP | disclosed |