Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 1/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.55 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 2/20 | 0.50 |
| ▸ | TSHR | P16473 | 2/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.50 |
| ▸ | IDO1 | P14902 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 3/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | CA12 | O43570 | 1/20 | 0.48 |
| ▸ | BRD4 | O60885 | 1/20 | 0.48 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.48 |
| ▸ | CA1 | P00915 | 1/20 | 0.48 |
| ▸ | CA2 | P00918 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6535275 | 0.90 | EPHX2 (0.57) | EPHX2SMN1; SMN2AOC3HTTTSHR | |
| SCHEMBL7393195 | 0.86 | EPHX2 (0.56) | EPHX2HTTCYP2C9IDO1KMT2A | |
| SCHEMBL6984766 | 0.85 | CYP4F2 (0.64) | SMN1; SMN2AOC3HTTCYP2C9KMT2A | |
| SCHEMBL22922181 | 0.85 | CYP4F2 (0.59) | EPHX2HTTTSHRIDO1KMT2A | |
| SCHEMBL14717782 | 0.84 | EPHX2 (0.56) | EPHX2HTTTSHRIDO1KMT2A | |
| SCHEMBL10750700 | 0.84 | ALDH1A1 (0.57) | SMN1; SMN2AOC3HTTTSHRCYP2C9 | |
| SCHEMBL12510584 | 0.84 | SMN1; SMN2 (0.53) | EPHX2SMN1; SMN2AOC3HTTL3MBTL1 | |
| SCHEMBL29622962 | 0.83 | AOC3 (0.67) | SMN1; SMN2AOC3HTTTSHRL3MBTL1 | |
| SCHEMBL29622963 | 0.83 | AOC3 (0.67) | SMN1; SMN2AOC3HTTTSHRL3MBTL1 | |
| SCHEMBL11803965 | 0.82 | AOC3 (0.54) | SMN1; SMN2AOC3HTTTSHRCYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 39 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112824421-A | Chiral phosphine-phosphoramidite ligand and preparation method and application thereof | 中国科学院大连化学物理研究所 | 2021-05-21 | — | — | CN | disclosed |
| EP-1606268-B1 | 5,10-DIHYDRO-11H-DIBENZO[B,E][1,4]DIAZEPIN-11-ONE AS KINASE INHIBITORS | ABBVIE INC (US) | 2015-05-20 | — | — | EP | disclosed |
| US-8475984-B1 | Image holding member for image forming apparatus, process cartridge, and image forming apparatus | FUJI XEROX CO., LTD. (JP) | 2013-07-02 | — | — | US | disclosed |
| US-20130164662-A1 | IMAGE HOLDING MEMBER FOR IMAGE FORMING APPARATUS, PROCESS CARTRIDGE, AND IMAGE FORMING APPARATUS | FUJI XEROX CO., LTD. (JP) | 2013-06-27 | — | — | US | disclosed |
| US-8445900-B2 | Organic eletroluminescent element including polyester electronic material and display device including the same | FUJI XEROX CO., LTD. (JP) | 2013-05-21 | — | — | US | disclosed |
| US-20130043461-A1 | ORGANIC ELECTROLUMINESCENT ELEMENT AND DISPLAY MEDIUM | FUJI XEROX CO., LTD. (JP) | 2013-02-21 | — | — | US | disclosed |
| US-20130032789-A1 | ORGANIC ELECTROLUMINESCENT ELEMENT AND DISPLAY MEDIUM | FUJI XEROX CO., LTD. (JP) | 2013-02-07 | — | — | US | disclosed |
| US-8264140-B2 | Organic electroluminescence element and display device | FUJI XEROX CO., LTD. (JP) | 2012-09-11 | — | — | US | disclosed |
| US-8102113-B2 | Quinoxaline-containing compounds and polymers thereof | FUJI XEROX CO., LTD. (JP) | 2012-01-24 | — | — | US | disclosed |
| US-8102113-B2 | Quinoxaline-containing compounds and polymers thereof | FUJI XEROX CO., LTD. (JP) | 2012-01-24 | — | — | US | disclosed |
| US-20080306239-A1 | QUINOXALINE-CONTAINING COMPOUNDS AND POLYMERS THEREOF | FUJI XEROX CO., LTD. (JP) | 2008-12-11 | — | — | US | disclosed |
| CN-101318940-A | Quinoxaline-containing compounds and polymers thereof | FUJI XEROX CO LTD (JP) | 2008-12-10 | — | — | CN | disclosed |
| US-7456169-B2 | Heterocyclic kinase inhibitors | ABBOTT LABORATORIES INC. (US) | 2008-11-25 | — | — | US | disclosed |
| US-20070254867-A1 | Heterocyclic Kinase Inhibitors | ABBVIE INC. | 2007-11-01 | — | — | US | disclosed |
| US-20070252519-A1 | Novel thiophene-containing compound and thiophene-containing compound polymer, organic electroluminescent device, production method thereof, and image display medium | FUJI XEROX CO., LTD. (JP) | 2007-11-01 | — | — | US | disclosed |
| US-20070252519-A1 | Novel thiophene-containing compound and thiophene-containing compound polymer, organic electroluminescent device, production method thereof, and image display medium | FUJI XEROX CO., LTD. (JP) | 2007-11-01 | — | — | US | disclosed |
| US-7153980-B2 | Thiophene-containing compound and thiophene-containing compound polymer | FUJI XEROX CO., LTD. (JP) | 2006-12-26 | — | — | US | disclosed |
| US-20050059730-A1 | Thiophene-containing compound and thiophene-containing compound polymer | FUJIFILM BUSINESS INNOVATION CORP. (JP) | 2005-03-17 | — | — | US | disclosed |
| US-20040254159-A1 | Heterocyclic kinase inhibitors | ABBOTT LABORATORIES | 2004-12-16 | — | — | US | disclosed |
| EP-0604800-A1 | 4- 4- 4-(carboxyalkyl)-phenyl amino carbonyl -phenyl -piperedines as aggregation inhibitors | Dr. Karl Thomae GmbH (DE) | 1994-07-06 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040254159-A1 | Heterocyclic kinase inhibitors | MAP3K20, MAP3K19, MAP3K1 | EPHX2 2654/4885SMN1; SMN2 3469/4885AOC3 3772/4885 |
| US-20080306239-A1 | QUINOXALINE-CONTAINING COMPOUNDS AND POLYMERS THEREOF | ARL1, NMRAL1, PDXK | EPHX2 4102/4885SMN1; SMN2 3205/4885AOC3 1054/4885 |
| US-20050059730-A1 | Thiophene-containing compound and thiophene-containing compound polymer | SLCO4C1, SLCO2A1, SLCO2B1 | EPHX2 1712/4885SMN1; SMN2 3960/4885AOC3 1171/4885 |
| US-20070252519-A1 | Novel thiophene-containing compound and thiophene-containing compound polymer, organic electroluminescent device, production method thereof, and image display medium | ARL1, NOD1, NLRP1 | EPHX2 2733/4885SMN1; SMN2 3896/4885AOC3 427/4885 |
| US-20070254867-A1 | Heterocyclic Kinase Inhibitors | MAP3K20, MAP3K19, MAP4K2 | EPHX2 2464/4885SMN1; SMN2 3562/4885AOC3 3808/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.