Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.42 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.42 |
| ▸ | GRIA3 | P42263 | 1/20 | 0.42 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.42 |
| ▸ | GRIK5 | Q16478 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | CA12 | O43570 | 6/20 | 0.38 |
| ▸ | CA9 | Q16790 | 6/20 | 0.38 |
| ▸ | DRD2 | P14416 | 1/20 | 0.38 |
| ▸ | DRD3 | P35462 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 5/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12657433 | 0.96 | LMNA (0.53) | LMNACYP1A2KDM4EGRIA1GRIA2 | |
| SCHEMBL16574249 | 0.91 | LMNA (0.62) | LMNACYP1A2KDM4EGRIA1GRIA2 | |
| SCHEMBL21129745 | 0.83 | LMNA (0.51) | LMNACYP1A2KDM4EGRIA1GRIA2 | |
| SCHEMBL19382510 | 0.83 | LMNA (0.52) | LMNACYP1A2KDM4EGRIA1GRIA2 | |
| SCHEMBL21129746 | 0.78 | LMNA (0.45) | LMNACYP1A2KDM4EGRIA1GRIA2 | |
| SCHEMBL21130046 | 0.78 | LMNA (0.44) | LMNACYP1A2KDM4EGRIA1GRIA2 | |
| SCHEMBL14520034 | 0.76 | LMNA (0.52) | LMNACYP1A2KDM4EGRIA1GRIA2 | |
| SCHEMBL290461 | 0.75 | SMN1; SMN2 (0.40) | LMNAKMT2AGAASMN1; SMN2 | |
| SCHEMBL12630504 | 0.74 | LMNA (0.59) | LMNACYP1A2KDM4EGRIA1GRIA2 | |
| SCHEMBL28687653 | 0.74 | LMNA (0.49) | LMNACYP1A2KDM4EGRIA1GRIA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9702869-B2 | Assays, antibodies, immunogens and compositions related to 5-FU | DEFINED DIAGNOSTICS, LLC (US) | 2017-07-11 | — | — | US | disclosed |
| US-20150079612-A1 | Assays, Antibodies, Immunogens and Compositions Related to 5-FU | PHARMA CINQ, LLC | 2015-03-19 | — | — | US | disclosed |
| US-20150079612-A1 | Assays, Antibodies, Immunogens and Compositions Related to 5-FU | PHARMA CINQ, LLC | 2015-03-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150079612-A1 | Assays, Antibodies, Immunogens and Compositions Related to 5-FU | DPYD, MTHFD1, DHFR | LMNA 4639/4885CYP1A2 2470/4885KDM4E 3817/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.