Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.50 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.50 |
| ▸ | DRD2 | P14416 | 1/20 | 0.45 |
| ▸ | DRD1 | P21728 | 1/20 | 0.45 |
| ▸ | DRD4 | P21917 | 1/20 | 0.45 |
| ▸ | DRD5 | P21918 | 1/20 | 0.45 |
| ▸ | DRD3 | P35462 | 1/20 | 0.45 |
| ▸ | UNG | P13051 | 1/20 | 0.45 |
| ▸ | KMO | O15229 | 1/20 | 0.43 |
| ▸ | PDE4A | P27815 | 2/20 | 0.42 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.42 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.42 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.42 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.41 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.41 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.40 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.40 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10373192 | 0.87 | DRD2 (0.54) | DRD2DRD1DRD4DRD5DRD3 | |
| SCHEMBL12212992 | 0.80 | NPC1 (0.62) | NPC1RAB9AAKR1C3AKR1C1PDE4A | |
| SCHEMBL12212988 | 0.80 | NPC1 (0.62) | NPC1RAB9AAKR1C3AKR1C1PDE4A | |
| SCHEMBL3437970 | 0.80 | DRD2 (0.58) | DRD2DRD1DRD4DRD5DRD3 | |
| SCHEMBL3438198 | 0.78 | DRD2 (0.57) | DRD2DRD1DRD4DRD5DRD3 | |
| SCHEMBL21731690 | 0.78 | NPC1 (0.54) | NPC1RAB9AAKR1C3AKR1C1DRD4 | |
| SCHEMBL7715894 | 0.78 | NPC1 (0.54) | NPC1RAB9AAKR1C3AKR1C1KMO | |
| SCHEMBL664284 | 0.77 | NPC1 (0.79) | NPC1RAB9AAKR1C3AKR1C1PDE4A | |
| SCHEMBL3516198 | 0.77 | NPC1 (0.79) | NPC1RAB9AAKR1C3AKR1C1PDE4A | |
| SCHEMBL2511695 | 0.77 | NPC1 (0.79) | NPC1RAB9AAKR1C3AKR1C1PDE4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9464166-B2 | Production and use of 3,4' and 4,4'-dimethylbiphenyl isomers | EXXONMOBIL CHEMICAL PATENTS INC. (US) | 2016-10-11 | — | — | US | disclosed |
| US-20150080546-A1 | Production and Use of 3,4' and 4,4'-Dimethylbiphenyl Isomers | EXXONMOBIL CHEMICAL PATENTS INC. | 2015-03-19 | — | — | US | disclosed |
| US-20150080545-A1 | Production and Use of 3,4' and 4,4'-Dimethylbiphenyl Isomers | EXXONMOBIL CHEMICAL PATENTS INC. | 2015-03-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150080546-A1 | Production and Use of 3,4' and 4,4'-Dimethylbiphenyl Isomers | CYP4B1, HPD, DDT | NPC1 4871/4885RAB9A 4370/4885AKR1C3 187/4885 |
| US-20150080545-A1 | Production and Use of 3,4' and 4,4'-Dimethylbiphenyl Isomers | CYP4B1, HPD, DDT | NPC1 4871/4885RAB9A 4370/4885AKR1C3 187/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.