Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRA | P19793 | 5/20 | 0.46 |
| ▸ | NR1H2 | P55055 | 5/20 | 0.46 |
| ▸ | NR1H3 | Q13133 | 5/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | CA9 | Q16790 | 1/20 | 0.41 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.41 |
| ▸ | ATR | Q13535 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | MYC | P01106 | 1/20 | 0.40 |
| ▸ | CNR1 | P21554 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16455382 | 0.92 | RXRA (0.47) | RXRANR1H2NR1H3NPC1ALDH1A1 | |
| SCHEMBL16455251 | 0.90 | RXRA (0.46) | RXRANR1H2NR1H3NPC1ALDH1A1 | |
| SCHEMBL16455383 | 0.84 | RXRA (0.53) | RXRANR1H2NR1H3NPC1ALDH1A1 | |
| SCHEMBL16455474 | 0.84 | NR1H2 (0.46) | RXRANR1H2NR1H3NPC1ALDH1A1 | |
| SCHEMBL16455631 | 0.82 | RXRA (0.52) | RXRANR1H2NR1H3NPC1ALDH1A1 | |
| SCHEMBL16455632 | 0.82 | NR1H2 (0.44) | RXRANR1H2NR1H3NPC1ALDH1A1 | |
| SCHEMBL15229733 | 0.81 | RXRA (0.56) | RXRANR1H2NR1H3NPC1ALDH1A1 | |
| SCHEMBL16455485 | 0.81 | ALDH1A1 (0.39) | RXRANR1H2NR1H3NPC1ALDH1A1 | |
| SCHEMBL16455255 | 0.81 | NR1H2 (0.48) | RXRANR1H2NR1H3NPC1ALDH1A1 | |
| SCHEMBL16452679 | 0.80 | NPC1 (0.49) | NPC1ALDH1A1RAB9ACA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8987318-B2 | Liver X receptor (LXR) modulators for the treatment of dermal diseases, disorders and conditions | ALEXAR THERAPEUTICS, INC. (US) | 2015-03-24 | — | — | US | disclosed |