Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHFR | P00374 | 11/20 | 0.57 |
| ▸ | TYMS | P04818 | 4/20 | 0.57 |
| ▸ | ATIC | P31939 | 3/20 | 0.57 |
| ▸ | GART | P22102 | 3/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.57 |
| ▸ | MEN1 | O00255 | 2/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.57 |
| ▸ | POLB | P06746 | 2/20 | 0.57 |
| ▸ | HPGD | P15428 | 2/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.57 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.57 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.57 |
| ▸ | GAA | P10253 | 1/20 | 0.57 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.57 |
| ▸ | TSHR | P16473 | 1/20 | 0.57 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.57 |
| ▸ | TLR4 | O00206 | 1/20 | 0.57 |
| ▸ | LMNA | P02545 | 1/20 | 0.57 |
| ▸ | TP53 | P04637 | 1/20 | 0.57 |
| ▸ | GLA | P06280 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28344641 | 0.95 | DHFR (0.57) | DHFRTYMSATICGARTKDM4E | |
| SCHEMBL28885296 | 0.94 | DHFR (0.56) | DHFRTYMSATICGARTKDM4E | |
| SCHEMBL29190442 | 0.93 | DHFR (0.57) | DHFRTYMSATICGARTKDM4E | |
| SCHEMBL28151272 | 0.93 | DHFR (0.55) | DHFRTYMSATICGARTKDM4E | |
| SCHEMBL338037 | 0.92 | DHFR (0.57) | DHFRTYMSATICGARTKDM4E | |
| SCHEMBL9771346 | 0.92 | DHFR (0.54) | DHFRTYMSATICGARTKDM4E | |
| SCHEMBL28379436 | 0.92 | DHFR (0.54) | DHFRTYMSATICGARTKDM4E | |
| SCHEMBL2029113 | 0.92 | DHFR (0.54) | DHFRTYMSATICGARTKDM4E | |
| SCHEMBL25167471 | 0.91 | DHFR (0.57) | DHFRTYMSATICGARTKDM4E | |
| SCHEMBL869876 | 0.91 | DHFR (0.57) | DHFRTYMSATICGARTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107998404-B | Folic acid targeting vector loaded with anticancer drug and preparation method and application thereof | 浙江大学 | 2021-05-04 | — | — | CN | disclosed |
| CN-108273068-A | Load the folate-targeted carrier and its preparation method and application of Epigallo-catechin gallate (EGCG) | 浙江大学 | 2018-07-13 | — | — | CN | disclosed |
| CN-108144068-A | Load folate-targeted carrier of monosubstituted Epigallo-catechin gallate (EGCG) palmitate and its preparation method and application | 浙江大学 | 2018-06-12 | — | — | CN | disclosed |
| CN-107998404-A | A kind of folate-targeted carrier for loading cancer therapy drug and its preparation method and application | 浙江大学 | 2018-05-08 | — | — | CN | disclosed |
| US-20150086976-A1 | SELF-CATALYTIC REACTION BASED ASSAY | UTAH STATE UNIVERSITY (US) | 2015-03-26 | — | — | US | disclosed |