Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHFR | P00374 | 8/20 | 0.54 |
| ▸ | GART | P22102 | 5/20 | 0.54 |
| ▸ | TYMS | P04818 | 4/20 | 0.54 |
| ▸ | ATIC | P31939 | 3/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.54 |
| ▸ | MEN1 | O00255 | 2/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.54 |
| ▸ | POLB | P06746 | 2/20 | 0.54 |
| ▸ | HPGD | P15428 | 2/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.54 |
| ▸ | GAA | P10253 | 1/20 | 0.54 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.54 |
| ▸ | TSHR | P16473 | 1/20 | 0.54 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.54 |
| ▸ | TLR4 | O00206 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | TP53 | P04637 | 1/20 | 0.54 |
| ▸ | GLA | P06280 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28379436 | 0.92 | DHFR (0.54) | DHFRGARTTYMSATICKDM4E | |
| SCHEMBL28344641 | 0.92 | DHFR (0.57) | DHFRGARTTYMSATICKDM4E | |
| SCHEMBL16583122 | 0.92 | DHFR (0.57) | DHFRGARTTYMSATICKDM4E | |
| SCHEMBL28885296 | 0.91 | DHFR (0.56) | DHFRGARTTYMSATICKDM4E | |
| SCHEMBL29190442 | 0.90 | DHFR (0.57) | DHFRGARTTYMSATICKDM4E | |
| SCHEMBL28151272 | 0.89 | DHFR (0.55) | DHFRGARTTYMSATICKDM4E | |
| SCHEMBL338037 | 0.89 | DHFR (0.57) | DHFRGARTTYMSATICKDM4E | |
| SCHEMBL9771346 | 0.89 | DHFR (0.54) | DHFRGARTTYMSATICKDM4E | |
| SCHEMBL25167471 | 0.88 | DHFR (0.57) | DHFRGARTTYMSATICKDM4E | |
| SCHEMBL869876 | 0.88 | DHFR (0.57) | DHFRGARTTYMSATICKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 43 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101903037-A | Method of administering conjugates | ENDOCYTE INC | 2010-12-01 | — | — | CN | claimed |
| US-20080248553-A1 | Production of Bioavailable Folic Acid | CAMPINA B.V. (NL) | 2008-10-09 | — | — | US | claimed |
| US-20040214261-A1 | Production of bioavailable folic acid | CAMPINA B.V. (NL) | 2004-10-28 | — | — | US | claimed |
| EP-1392816-A1 | PRODUCTION OF BIOAVAILABLE FOLIC ACID | Stichting Top-Instituut Voedselwetenschappen (NL) | 2004-03-03 | — | — | EP | claimed |
| WO-2002097063-A1 | PRODUCTION OF BIOAVAILABLE FOLIC ACID | CAMPINA B.V. (NL) | 2002-12-05 | — | — | WO | claimed |
| EP-1262541-A1 | Production of bioavailable folic acid | Stichting Top-Instituut Voedselwetenschappen (NL) | 2002-12-04 | — | — | EP | claimed |
| US-12263192-B2 | Compositions for management of disorders of the gastrointestinal tract | PANTHERYX, INC. (US) | 2025-04-01 | — | — | US | disclosed |
| CN-110730908-B | Engineered cells expressing Prostate Specific Membrane Antigen (PSMA) or modified versions thereof and related methods | 朱诺治疗学股份有限公司 | 2025-01-21 | — | — | CN | disclosed |
| WO-2022235976-A1 | MULTITARGETING RNA COMPOSITIONS | SYSTEMS ONCOLOGY, LLC (US) | 2022-11-10 | — | — | WO | disclosed |
| US-20220047646-A1 | COMPOSITIONS FOR MANAGEMENT OF DISORDERS OF THE GASTROINTESTINAL TRACT | PANTHERYX, INC. | 2022-02-17 | — | — | US | disclosed |
| US-20210254046-A1 | GENERATION OF SYNTHETIC GENOMES | ETONBIO, INC. | 2021-08-19 | — | — | US | disclosed |
| US-11085037-B2 | Generation of synthetic genomes | CODEX DNA, INC. (US) | 2021-08-10 | — | — | US | disclosed |
| EP-3714906-A1 | TREATMENT OF PROLIFERATIVE DISORDERS USING RADIOLABELLED ANTIBODIES TO PSMA | Cornell University (US) | 2020-09-30 | — | — | EP | disclosed |
| WO-2002097063-A1 | PRODUCTION OF BIOAVAILABLE FOLIC ACID | CAMPINA B.V. (NL) | 2002-12-05 | — | — | WO | disclosed |
| WO-2002097063-A1 | PRODUCTION OF BIOAVAILABLE FOLIC ACID | CAMPINA B.V. (NL) | 2002-12-05 | — | — | WO | disclosed |
| EP-1262541-A1 | Production of bioavailable folic acid | Stichting Top-Instituut Voedselwetenschappen (NL) | 2002-12-04 | — | — | EP | disclosed |
| EP-1262541-A1 | Production of bioavailable folic acid | Stichting Top-Instituut Voedselwetenschappen (NL) | 2002-12-04 | — | — | EP | disclosed |
| WO-2002076937-A2 | AMINOBENZOPYRAN DERIVATIVES AND COMPOSITIONS | SONUS PHARMACEUTICALS, INC. (US) | 2002-10-03 | — | — | WO | disclosed |
| US-20020009734-A1 | Mutations in human glutamate carboxypeptidase II gene impacting folate metabolism, and detection of affected individuals | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2002-01-24 | — | — | US | disclosed |
| WO-2001068897-A2 | MUTATIONS IN HUMAN GLUTAMATE CARBOXYPEPTIDASE II GENE IMPACTING FOLATE METABOLISM, AND DETECTION OF AFFECTED INDIVIDUALS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2001-09-20 | — | — | WO | disclosed |