Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 1/20 | 0.35 |
| ▸ | LPAR1 | Q92633 | 5/20 | 0.32 |
| ▸ | LPAR3 | Q9UBY5 | 5/20 | 0.32 |
| ▸ | LPAR6 | P43657 | 3/20 | 0.32 |
| ▸ | LPAR4 | Q99677 | 3/20 | 0.32 |
| ▸ | LPAR5 | Q9H1C0 | 3/20 | 0.32 |
| ▸ | LPAR2 | Q9HBW0 | 3/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1658385 | 1.00 | PTPN1 (0.35) | PTPN1LPAR1LPAR3LPAR6LPAR4 | |
| SCHEMBL1657552 | 0.95 | LMNA (0.34) | PTPN1LPAR1LPAR3LPAR6LPAR4 | |
| SCHEMBL1657554 | 0.95 | LMNA (0.34) | PTPN1LPAR1LPAR3LPAR6LPAR4 | |
| SCHEMBL1658205 | 0.89 | PTPN1 (0.33) | PTPN1ALDH1A1MEN1CYP3A4ALOX15 | |
| SCHEMBL1658207 | 0.89 | PTPN1 (0.33) | PTPN1ALDH1A1MEN1CYP3A4ALOX15 | |
| SCHEMBL1661326 | 0.81 | MEN1 (0.34) | PTPN1ALDH1A1MEN1CYP3A4ALOX15 | |
| SCHEMBL1661329 | 0.81 | MEN1 (0.34) | PTPN1ALDH1A1MEN1CYP3A4ALOX15 | |
| SCHEMBL1658741 | 0.80 | PTPN1 (0.43) | PTPN1ALDH1A1MEN1CYP3A4ALOX15 | |
| SCHEMBL1658742 | 0.80 | PTPN1 (0.43) | PTPN1ALDH1A1MEN1CYP3A4ALOX15 | |
| SCHEMBL1782371 | 0.77 | CTSK (0.33) | ALDH1A1CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8632792-B2 | Cooling sensation agent composition and sensory stimulation agent composition | TAKASAGO INTERNATIONAL CORPORATION (JP) | 2014-01-21 | — | — | US | disclosed |
| US-20130131169-A1 | COOLING SENSATION AGENT COMPOSITION, SENSORY STIMULATION AGENT COMPOSITION AND USE OF THE SAME | TAKASAGO INTERNATIONAL CORPORATION (JP) | 2013-05-23 | — | — | US | disclosed |
| US-8377458-B2 | Cooling sensation agent composition, sensory stimulation agent composition and use of the same | TAKASAGO INTERNATIONAL CORPORATION (JP) | 2013-02-19 | — | — | US | disclosed |
| US-20110117147-A1 | COOLING SENSATION AGENT COMPOSITION AND SENSORY STIMULATION AGENT COMPOSITION | TAKASAGO INTERNATIONAL CORPORATION (JP) | 2011-05-19 | — | — | US | disclosed |
| US-20110081393-A1 | COOLING SENSATION AGENT COMPOSITION, SENSORY STIMULATION AGENT COMPOSITION AND USE OF THE SAME | TAKASAGO INTERNATIONAL CORPORATION | 2011-04-07 | — | — | US | disclosed |
| WO-2009123355-A2 | COOLING SENSATION AGENT COMPOSITION AND SENSORY STIMULATION AGENT COMPOSITION | TAKASAGO INTERNATIONAL CORPORATION (JP) | 2009-10-08 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110117147-A1 | COOLING SENSATION AGENT COMPOSITION AND SENSORY STIMULATION AGENT COMPOSITION | TRPA1, HRH1, HRH2 | PTPN1 4528/4885LPAR1 3486/4885LPAR3 3463/4885 |
| US-20110081393-A1 | COOLING SENSATION AGENT COMPOSITION, SENSORY STIMULATION AGENT COMPOSITION AND USE OF THE SAME | TRPA1, TRPV1, TRPM4 | PTPN1 4088/4885LPAR1 4185/4885LPAR3 4407/4885 |
| US-20130131169-A1 | COOLING SENSATION AGENT COMPOSITION, SENSORY STIMULATION AGENT COMPOSITION AND USE OF THE SAME | TRPA1, TRPV1, TRPM4 | PTPN1 4088/4885LPAR1 4185/4885LPAR3 4407/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.