SCHEMBL16585474

SCHEMBL16585474

O=C(CCO)CC(=O)C(=O)O

nearest known ligand 0.52

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
HAO1 Q9UJM8 3/20 0.52
OR51E2 Q9H255 2/20 0.43
EGLN1 Q9GZT9 2/20 0.39
MAPK1 P28482 1/20 0.39
SLC13A3 Q8WWT9 1/20 0.39
FEN1 P39748 5/20 0.34
ERCC5 P28715 4/20 0.34
PTPN1 P18031 1/20 0.34
KDM4E B2RXH2 1/20 0.33
KDM6B O15054 1/20 0.33
KDM5C P41229 1/20 0.33
PHF8 Q9UPP1 1/20 0.33
KDM2A Q9Y2K7 1/20 0.33
CAMK2A Q9UQM7 1/20 0.33
FNTA P49354 1/20 0.32
FNTB P49356 1/20 0.32
GPR84 Q9NQS5 1/20 0.31
FFAR1 O14842 1/20 0.31
FFAR4 Q5NUL3 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7096118 0.80 HAO1 (0.67) HAO1OR51E2EGLN1MAPK1SLC13A3
SCHEMBL9682879 0.78 EGLN1 (0.60) HAO1OR51E2EGLN1MAPK1SLC13A3
SCHEMBL1533922 0.77 OR51E2 (0.56) HAO1OR51E2EGLN1MAPK1SLC13A3
SCHEMBL418465 0.77
SCHEMBL247453 0.76 HAO1 (0.68) HAO1OR51E2EGLN1MAPK1SLC13A3
SCHEMBL16585547 0.76 HAO1 (0.50) HAO1OR51E2EGLN1MAPK1SLC13A3
SCHEMBL126796 0.76
SCHEMBL7798107 0.74 HAO1 (0.65) HAO1OR51E2EGLN1MAPK1SLC13A3
SCHEMBL285014 0.72 HAO1 (0.83) HAO1OR51E2PTPN1GPR84FFAR1
SCHEMBL28830010 0.72 HAO1 (0.63) HAO1OR51E2EGLN1MAPK1SLC13A3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12104160-B2 Production of 4,6-dihydroxy-2-oxo-hexanoic acid ZYMOCHEM, INC. (US) 2024-10-01 US disclosed
US-20220389433-A1 HIGH YIELD ROUTE FOR THE PRODUCTION OF COMPOUNDS FROM RENEWABLE SOURCES ZYMOCHEM, INC. 2022-12-08 US disclosed
US-20200255840-A1 HIGH YIELD ROUTE FOR THE PRODUCTION OF 1, 6-HEXANEDIOL ZYMOCHEM INC (US) 2020-08-13 US disclosed
US-20170044551-A1 HIGH YIELD ROUTE FOR THE PRODUCTION OF COMPOUNDS FROM RENEWABLE SOURCES ZYMOCHEM INC. 2017-02-16 US disclosed
EP-3047030-A2 A HIGH YIELD ROUTE FOR THE PRODUCTION OF COMPOUNDS FROM RENEWABLE SOURCES Zymochem Inc. (US) 2016-07-27 EP disclosed
CN-105745327-A High-yield route for producing compounds from renewable resources 兹莫克姆有限公司 2016-07-06 CN disclosed
WO-2015042201-A2 A HIGH YIELD ROUTE FOR THE PRODUCTION OF COMPOUNDS FROM RENEWABLE SOURCES ZYMOCHEM INC. (US) 2015-03-26 WO disclosed