Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HAO1 | Q9UJM8 | 2/20 | 0.63 |
| ▸ | CES2 | O00748 | 5/20 | 0.43 |
| ▸ | CES1 | P23141 | 5/20 | 0.43 |
| ▸ | HDAC3 | O15379 | 4/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 4/20 | 0.42 |
| ▸ | HDAC2 | Q92769 | 4/20 | 0.42 |
| ▸ | HDAC8 | Q9BY41 | 4/20 | 0.42 |
| ▸ | FFAR3 | O14843 | 3/20 | 0.42 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.37 |
| ▸ | CTSD | P07339 | 1/20 | 0.36 |
| ▸ | EGLN1 | Q9GZT9 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | SLC13A3 | Q8WWT9 | 1/20 | 0.35 |
| ▸ | OR51E2 | Q9H255 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | KDM6B | O15054 | 1/20 | 0.34 |
| ▸ | KDM5C | P41229 | 1/20 | 0.34 |
| ▸ | PHF8 | Q9UPP1 | 1/20 | 0.34 |
| ▸ | KDM2A | Q9Y2K7 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL247453 | 0.95 | HAO1 (0.68) | HAO1CES2CES1HDAC3HDAC1 | |
| SCHEMBL7798107 | 0.93 | HAO1 (0.65) | HAO1CES2CES1HDAC3HDAC1 | |
| SCHEMBL5667473 | 0.84 | CES2 (0.50) | HAO1CES2CES1HDAC3HDAC1 | |
| SCHEMBL1701664 | 0.82 | CES2 (0.53) | HAO1CES2CES1HDAC3HDAC1 | |
| SCHEMBL285014 | 0.81 | HAO1 (0.83) | HAO1CES2CES1TSHROR51E2 | |
| SCHEMBL22750315 | 0.80 | HDAC3 (0.52) | HAO1CES2CES1HDAC3HDAC1 | |
| SCHEMBL1318842 | 0.80 | HDAC3 (0.52) | HAO1CES2CES1HDAC3HDAC1 | |
| SCHEMBL1194076 | 0.79 | HAO1 (0.96) | HAO1CES2CES1TSHROR51E2 | |
| SCHEMBL7796552 | 0.79 | HAO1 (0.80) | HAO1CES2CES1TSHROR51E2 | |
| SCHEMBL3126473 | 0.79 | CES2 (0.50) | HAO1CES2CES1HDAC3HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106119113-A | For producing the biology of 1,3 butanediols | 基因组股份公司 | 2016-11-16 | — | — | CN | disclosed |
| CN-102625846-B | Organisms for the production of 1, 3-butanediol | 基因组股份公司 | 2016-08-03 | — | — | CN | disclosed |