Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGLN1 | Q9GZT9 | 5/20 | 0.60 |
| ▸ | OR51E2 | Q9H255 | 2/20 | 0.60 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.60 |
| ▸ | SLC13A3 | Q8WWT9 | 1/20 | 0.60 |
| ▸ | PHF8 | Q9UPP1 | 6/20 | 0.56 |
| ▸ | KDM2A | Q9Y2K7 | 6/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.56 |
| ▸ | KDM5C | P41229 | 4/20 | 0.56 |
| ▸ | KDM6B | O15054 | 2/20 | 0.56 |
| ▸ | HAO1 | Q9UJM8 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 4/20 | 0.50 |
| ▸ | ALKBH5 | Q6P6C2 | 1/20 | 0.50 |
| ▸ | SUCNR1 | Q9BXA5 | 1/20 | 0.50 |
| ▸ | GABRR1 | P24046 | 1/20 | 0.48 |
| ▸ | ACE | P12821 | 1/20 | 0.46 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.42 |
| ▸ | SLC15A2 | Q16348 | 1/20 | 0.39 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Oxaloacetate SCHEMBL5614074 | 0.82 | EGLN1 (0.67) | EGLN1OR51E2MAPK1SLC13A3PHF8 | |
| SCHEMBL4098641 | 0.82 | PHF8 (0.68) | EGLN1OR51E2MAPK1SLC13A3PHF8 | |
| SCHEMBL17024369 | 0.79 | PHF8 (0.65) | EGLN1OR51E2MAPK1SLC13A3PHF8 | |
| SCHEMBL30572348 | 0.79 | PHF8 (0.65) | EGLN1OR51E2MAPK1SLC13A3PHF8 | |
| SCHEMBL218098 | 0.79 | PHF8 (0.65) | EGLN1OR51E2MAPK1SLC13A3PHF8 | |
| Alpha-Ketoglutaric Acid SCHEMBL1966431 | 0.78 | EGLN1 (0.78) | EGLN1OR51E2MAPK1SLC13A3PHF8 | |
| SCHEMBL16585474 | 0.78 | HAO1 (0.52) | EGLN1OR51E2MAPK1SLC13A3PHF8 | |
| SCHEMBL20377443 | 0.77 | PHF8 (0.62) | EGLN1OR51E2MAPK1SLC13A3PHF8 | |
| SCHEMBL20377438 | 0.77 | PHF8 (0.62) | EGLN1OR51E2MAPK1SLC13A3PHF8 | |
| SCHEMBL6914036 | 0.77 | PHF8 (0.62) | EGLN1OR51E2MAPK1SLC13A3PHF8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5144050-A | Hydrogenation Catalysts | MONSANTO COMPANY (US) | 1992-09-01 | — | — | US | disclosed |
| WO-1991004734-A1 | PHARMACEUTICAL COMPOSITIONS CONTAINING 4,6-TIOXOHEPTANOIC ACID OR ITS DERIVATIVES | CETUS CORPORATION (US) | 1991-04-18 | — | — | WO | disclosed |
| WO-1990000049-A2 | IMMUNOSUPPRESSIVE ANALOGUES AND DERIVATIVES OF SUCCINYLACETONE | CETUS CORPORATION (US) | 1990-01-11 | — | — | WO | disclosed |