Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HAO1 | Q9UJM8 | 1/20 | 0.83 |
| ▸ | CES1 | P23141 | 6/20 | 0.52 |
| ▸ | CES2 | O00748 | 5/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | CA1 | P00915 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.41 |
| ▸ | PPARG | P37231 | 5/20 | 0.41 |
| ▸ | PPARD | Q03181 | 5/20 | 0.41 |
| ▸ | PPARA | Q07869 | 5/20 | 0.41 |
| ▸ | HDAC11 | Q96DB2 | 4/20 | 0.41 |
| ▸ | TSHR | P16473 | 3/20 | 0.41 |
| ▸ | GPR84 | Q9NQS5 | 3/20 | 0.41 |
| ▸ | TLR2 | O60603 | 2/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | FABP4 | P15090 | 2/20 | 0.41 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7796552 | 0.98 | HAO1 (0.80) | HAO1CES1CES2KMT2AMAPT | |
| SCHEMBL1194076 | 0.93 | HAO1 (0.96) | HAO1CES1CES2KMT2AMAPT | |
| SCHEMBL5474445 | 0.91 | HAO1 (1.00) | HAO1CES1CES2KMT2AMAPT | |
| SCHEMBL8741845 | 0.91 | HAO1 (1.00) | HAO1CES1CES2KMT2AMAPT | |
| SCHEMBL5468904 | 0.91 | HAO1 (1.00) | HAO1CES1CES2KMT2AMAPT | |
| SCHEMBL2528845 | 0.91 | HAO1 (1.00) | HAO1CES1CES2KMT2AMAPT | |
| SCHEMBL8074587 | 0.91 | HAO1 (1.00) | HAO1CES1CES2KMT2AMAPT | |
| SCHEMBL247453 | 0.85 | HAO1 (0.68) | HAO1CES1CES2ALDH1A1AKR1B1 | |
| SCHEMBL7798107 | 0.83 | HAO1 (0.65) | HAO1CES1CES2KMT2AMAPT | |
| SCHEMBL534933 | 0.82 | CES1 (0.58) | HAO1CES1CES2KMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 109 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230022727-A1 | MICROORGANISMS AND METHODS FOR THE BIOSYNTHESIS OF ADIPATE, HEXAMETHYLENEDIAMINE AND 6-AMINOCAPROIC ACID | GENOMATICA INC (US) | 2023-01-26 | — | — | US | claimed |
| US-20190330670-A1 | MICROORGANISMS AND METHODS FOR THE BIOSYNTHESIS OF ADIPATE, HEXAMETHYLENEDIAMINE AND 6-AMINOCAPROIC ACID | AGAIN BIO APS (DK) | 2019-10-31 | — | — | US | claimed |
| US-20130303723-A1 | MICROORGANISMS AND METHODS FOR THE BIOSYNTHESIS OF ADIPATE, HEXAMETHYLENEDIAMINE AND 6-AMINOCAPROIC ACID | AGAIN BIO APS (DK) | 2013-11-14 | — | — | US | claimed |
| WO-2012177721-A1 | MICROORGANISMS FOR PRODUCING 6-AMINOCAPROIC ACID | GENOMATICA, INC. (US) | 2012-12-27 | — | — | WO | claimed |
| EP-2427544-A1 | MICROORGANISMS AND METHODS FOR THE BIOSYNTHESIS OF ADIPATE, HEXAMETHYLENEDIAMINE AND 6-AMINOCAPROIC ACID | Genomatica, Inc. (US) | 2012-03-14 | — | — | EP | claimed |
| US-20100317069-A1 | MICROORGANISMS AND METHODS FOR THE BIOSYNTHESIS OF ADIPATE, HEXAMETHYLENEDIAMINE AND 6-AMINOCAPROIC ACID | AGAIN BIO APS (DK) | 2010-12-16 | — | — | US | claimed |
| WO-2010129936-A1 | MICROORGANISMS AND METHODS FOR THE BIOSYNTHESIS OF ADIPATE, HEXAMETHYLENEDIAMINE AND 6-AMINOCAPROIC ACID | GENOMATICA, INC. (US) | 2010-11-11 | — | — | WO | claimed |
| US-4298508-A | MERCAPTAN-CONTAINING | PHILLIPS PETROLEUM COMPANY (US) | 1981-11-03 | — | — | US | claimed |
| US-4224200-A | Polymer curing system, air-curable composition and method of preparing the composition | PHILLIPS PETROLEUM COMPANY (US) | 1980-09-23 | — | — | US | claimed |
| EP-0012182-A1 | Air curable, one package sealing composition, curing system, and method for curing mercaptan group-containing base materials | PHILLIPS PETROLEUM COMPANY (US) | 1980-06-25 | — | — | EP | claimed |
| US-12577591-B2 | Microorganisms and methods for increasing co-factors | GENOMATICA, INC. (US) | 2026-03-17 | — | — | US | disclosed |
| US-20260028651-A1 | METHOD OF PRODUCING & PROCESSING DIAMINES | AGAIN BIO APS (DK) | 2026-01-29 | — | — | US | disclosed |
| US-12503711-B2 | Method of producing and processing diamines to a diamine free base using a carbonate intermediate and an engineered microorganism | GENOMATICA, INC. (US) | 2025-12-23 | — | — | US | disclosed |
| WO-2025245342-A1 | METAL-FLUORIDE THIN FILMS AND DEPOSITION METHODS | LOTUS APPLIED TECHNOLOGY, LLC (US) | 2025-11-27 | — | — | WO | disclosed |
| US-20250361606-A1 | METAL-FLUORIDE THIN FILMS AND DEPOSITION METHODS | LOTUS APPLIED TECH LLC (US) | 2025-11-27 | — | — | US | disclosed |
| US-20050186341-A1 | Chemical vapor deposition of high conductivity, adherent thin films of ruthenium | TRUIST BANK, AS NOTES COLLATERAL AGENT | 2005-08-25 | — | — | US | disclosed |
| WO-1996012706-A1 | NOVEL ACID PYRAZOLE AND PYRAZOLONE DERIVATIVES FOR USE AS ENDOTHELIN RECEPTOR ANTAGONISTS | ROUSSEL UCLAF (FR) | 1996-05-02 | — | — | WO | disclosed |
| EP-0454843-A4 | METHOD AND APPARATUS FOR THE RAPID DEPOSITION BY CHEMICAL VAPOR DEPOSITION WITH LOW VAPOR PRESSURE REACTANTS | GEORGIA TECH RES INST (US) | 1994-12-28 | — | — | EP | disclosed |
| EP-0454843-A1 | METHOD AND APPARATUS FOR THE RAPID DEPOSITION BY CHEMICAL VAPOR DEPOSITION WITH LOW VAPOR PRESSURE REACTANTS | GEORGIA TECH RESEARCH CORPORATION (US) | 1991-11-06 | — | — | EP | disclosed |
| WO-1991007236-A1 | METHOD AND APPARATUS FOR THE RAPID DEPOSITION BY CHEMICAL VAPOR DEPOSITION WITH LOW VAPOR PRESSURE REACTANTS | GEORGIA TECH RESEARCH CORPORATION (US) | 1991-05-30 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20260028651-A1 | METHOD OF PRODUCING & PROCESSING DIAMINES | DDC, DAO, ODC1 | HAO1 282/4885CES1 1494/4885CES2 993/4885 |
| US-12577591-B2 | Microorganisms and methods for increasing co-factors | ABAT, HADHB, MMAB | HAO1 168/4885CES1 1054/4885CES2 1114/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.