Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCRTR1 | O43613 | 3/20 | 0.51 |
| ▸ | TAS1R3 | Q7RTX0 | 4/20 | 0.47 |
| ▸ | TAS1R1 | Q7RTX1 | 4/20 | 0.47 |
| ▸ | TAS1R2 | Q8TE23 | 4/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.43 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.43 |
| ▸ | PPIA | P62937 | 1/20 | 0.42 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.41 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.41 |
| ▸ | MGLL | Q99685 | 1/20 | 0.41 |
| ▸ | DPP4 | P27487 | 3/20 | 0.40 |
| ▸ | DPP7 | Q9UHL4 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17598751 | 0.86 | HCRTR1 (0.52) | HCRTR1TAS1R3TAS1R1TAS1R2LMNA | |
| SCHEMBL17598770 | 0.86 | P2RX7 (0.50) | HCRTR1TAS1R3TAS1R1TAS1R2GAA | |
| SCHEMBL15295032 | 0.84 | HCRTR1 (0.45) | HCRTR1TAS1R3TAS1R1TAS1R2LMNA | |
| SCHEMBL16451641 | 0.84 | HCRTR1 (0.45) | HCRTR1TAS1R3TAS1R1TAS1R2LMNA | |
| SCHEMBL16451640 | 0.84 | HCRTR1 (0.45) | HCRTR1TAS1R3TAS1R1TAS1R2LMNA | |
| SCHEMBL17799670 | 0.84 | HCRTR1 (0.45) | HCRTR1TAS1R3TAS1R1TAS1R2LMNA | |
| SCHEMBL15295033 | 0.84 | HCRTR1 (0.45) | HCRTR1TAS1R3TAS1R1TAS1R2LMNA | |
| SCHEMBL16220964 | 0.83 | HCRTR1 (0.51) | HCRTR1TAS1R3TAS1R1TAS1R2LMNA | |
| SCHEMBL16211716 | 0.83 | HCRTR1 (0.51) | HCRTR1TAS1R3TAS1R1TAS1R2LMNA | |
| SCHEMBL16220800 | 0.83 | HCRTR1 (0.51) | HCRTR1TAS1R3TAS1R1TAS1R2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160075653-A1 | NEMATICIDAL N-(PHENYLCYCLOALKYL)CARBOXAMIDES AND N-(PHENYLCYCLOALKYL)THIOCARBOXAMIDES | BAYER ANIMAL HEALTH GMBH (DE) | 2016-03-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160075653-A1 | NEMATICIDAL N-(PHENYLCYCLOALKYL)CARBOXAMIDES AND N-(PHENYLCYCLOALKYL)THIOCARBOXAMIDES | DNPH1, AADAC, NAAA | HCRTR1 1170/4885TAS1R3 2259/4885TAS1R1 2629/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.